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ADCY4 / Adenylate Cyclase 4

adenylate cyclase 4

ADCY4 / Adenylate Cyclase 4 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.

Gene Name: adenylate cyclase 4
Family/Subfamily: Adenylate cyclase , not assigned-Adenylate cyclase
Synonyms: ADCY4, Adenylate cyclase type IV, Adenylyl cyclase 4, Adenylate cyclase type 4, Adenylate cyclase 4, AC4, ATP pyrophosphate-lyase 4
Target Sequences: CAC37757.1 Q8NFM4

Publications (1)

1
VLA-4 phosphorylation during tumor and immune cell migration relies on its coupling to VEGFR2 and CXCR4 by syndecan-1. Oisun Jung, DeannaLee M Beauvais, Kristin M Adams, Alan C Rapraeger. Journal of cell science. 2019 Oct;132:jcs232645. [Full Text Article] [PubMed:31562188] [PMC:PMC6826009] Related Antibodies: LS-C200088.

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ADCY4 / Adenylate Cyclase 4 ELISA Kit
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0.625 - 40 ng/ml
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ADCY4 / Adenylate Cyclase 4 ELISA Kit
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96-Well Strip Plate
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0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).