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ADCY1 / Adenylate Cyclase 1

adenylate cyclase 1 (brain)

This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina.

Gene Name: adenylate cyclase 1 (brain)
Family/Subfamily: Adenylate cyclase , not assigned-Adenylate cyclase
Synonyms: ADCY1, 3,5-cyclic AMP synthetase, Adenylate cyclase type I, AC1, Adenylate cyclase type 1, Adenylyl cyclase 1, ATP pyrophosphate-lyase 1, Adenyl cyclase, Adenylate cyclase 1 (brain), Adenylate cyclase, type i, ATP pyrophosphate-lyase
Target Sequences: L05500 AAA02907.1 Q08828

Publications (1)

1
Amplified fluorogenic immunoassay for early diagnosis and monitoring of Alzheimer's disease from tear fluid. Sojeong Lee, Eunjung Kim, Chae-Eun Moon, Chaewon Park, Jong-Woo Lim, Minseok Baek, Moo-Kwang Shin, Jisun Ki, Hanna Cho, Yong Woo Ji, Seungjoo Haam. Nature communications. 2023 December;14:8153. [Full Text Article] [PubMed:38071202] [PMC:PMC10710446]

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Products
Antibodies (23)
Primary (23)
ADCY1 / Adenylate Cyclase 1 (23)
Human (15)
Mouse (14)
Rat (2)
Bovine (1)
IHC (7)
IHC-P (4)
WB (18)
ELISA (9)
IF (2)
Peptide-ELISA (2)
rabbit (23)
Product Group
IHCPlus (2)
IgG (13)
polyclonal pc (23)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
aa303-569 (8)
200-280 aa, Internal (1)
Internal (1)
aa230-280 (1)
aa231-280 (1)
aa416-610 (1)
No (23)
ADCY1 / Adenylate Cyclase 1 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal (aa230-280) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of A Cyclase I antibody
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal (200-280 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot analysis of extracts of various cells.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ADCY1 / Adenylate Cyclase 1 Antibody - Immunohistochemistry of paraffin-embedded Human brain using ADCY1 Polyclonal Antibody at dilution of 1:60.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ADCY1 / Adenylate Cyclase 1 Antibody - Anti-ADCY1 / Adenylate Cyclase 1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal (aa231-280) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
ADCY1 / Adenylate Cyclase 1 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer at dilution of 1:100
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal (aa416-610) Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ADCY1 / Adenylate Cyclase 1 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ADCY1 / Adenylate Cyclase 1 Antibody - Immunohistochemical analysis of Adenylate Cyclase 1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
ADCY1 / Adenylate Cyclase 1 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using ADCY1 Polyclonal Antibody at dilution of 1:60.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot analysis of extracts from COLO205 cells, using ADCY1 antibody.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of recombinant ADCY1 / Adenylate Cyclase 1.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Mouse Polyclonal (aa303-569) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of recombinant ADCY1 / Adenylate Cyclase 1.
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Mouse Polyclonal (aa303-569) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of recombinant ADCY1 / Adenylate Cyclase 1.
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Mouse Polyclonal (aa303-569) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of recombinant ADCY1 / Adenylate Cyclase 1.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Mouse Polyclonal (aa303-569) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of recombinant ADCY1 / Adenylate Cyclase 1.
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Mouse Polyclonal (aa303-569) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of recombinant ADCY1 / Adenylate Cyclase 1.
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Mouse Polyclonal (aa303-569) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of recombinant ADCY1 / Adenylate Cyclase 1.
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Mouse Polyclonal (aa303-569) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
ADCY1 / Adenylate Cyclase 1 Antibody - Western blot of recombinant ADCY1 / Adenylate Cyclase 1.
Select
ADCY1 / Adenylate Cyclase 1 Rabbit anti-Mouse Polyclonal (aa303-569) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$497; 200 µl/$632; 500 µl/$1,132; 1 ml/$1,369; 2 ml/$1,916; 5 ml/$3,592
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ADCY1 / Adenylate Cyclase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).