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ADCK4
aarF domain containing kinase 4
ADCK4 is a protein with two copies of a domain found in protein kinases. The encoded protein has a complete protein kinase catalytic domain, and a truncated domain that contains only the active and binding sites of the protein kinase domain, however, it is not known whether the protein has any kinase activity. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | aarF domain containing kinase 4 |
| Family/Subfamily: | Protein Kinase , ABC1 |
| Synonyms: | ADCK4, COQ8 |
| Target Sequences: | NM_024876 AAH13114.2 Q96D53 |
Publications (3)
1
Mutations in COQ8B (ADCK4) found in patients with steroid-resistant nephrotic syndrome alter COQ8B function. Vazquez Fonseca L, Doimo M, Calderan C, Desbats MA, Acosta MJ, Cerqua C, Cassina M, Ashraf S, Hildebrandt F, Sartori G, Navas P, Trevisson E, Salviati L. Human mutation. 2018 March;39:406-414. (Human)
[Full Text Article]
[PubMed:29194833]
[PMC:PMC5838795]
Related Antibodies: LS-C119206.
2
ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment. Eugen Widmeier, Seyoung Yu, Anish Nag, Youn Wook Chung, Makiko Nakayama, Lucía Fernández-Del-Río, Hannah Hugo, David Schapiro, Florian Buerger, Won-Il Choi, Martin Helmstädter, Jae-Woo Kim, Ji-Hwan Ryu, Min Goo Lee, Catherine F Clarke, Friedhelm Hildebrandt, Heon Yung Gee. Journal of the American Society of Nephrology : JASN. 2020 June;31:1191-1211. [Full Text Article]
[PubMed:32381600]
[PMC:PMC7269352]
Related Antibodies: LS-C119206.
3
Identification of a common polymorphism in COQ8B acting as a modifier of thoracic aortic aneurysm severity. Benjamin J Landis, Dongbing Lai, Dong-Chuan Guo, Joel S Corvera, Muhammad T Idrees, Henry W Stadler, Christian Cuevas, Gavin U Needler, Courtney E Vujakovich, Dianna M Milewicz, Robert B Hinton, Stephanie M Ware. HGG advances. 2022 January;3: [Full Text Article]
[PubMed:34917985]
[PMC:PMC8670066]
Related Antibodies: LS-C119206.
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Type
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Primary
(25)
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(2)
Target
ADCK4
(32)
Reactivity
Human
(26)
Mouse
(7)
Rat
(6)
Application
IHC
(4)
IHC-P
(3)
WB
(21)
ELISA
(12)
ICC
(1)
IF
(6)
Peptide-ELISA
(3)
Host
rabbit
(19)
mouse
(6)
Product Group
IHCPlus
(2)
Isotype
IgG
(19)
IgG2b,k
(6)
Clonality
monoclonal mc
(6)
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(19)
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(1)
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(2)
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(3)
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(3)
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(3)
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(2)
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(12)
Epitope
1-80 aa, N-terminal
(1)
aa141-460
(1)
aa231-544
(1)
aa31-80
(1)
aa445-545
(1)
aa6-55
(1)
Publications
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(31)
Yes
(1)
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(1)
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(1)
GST, N-terminus
(1)
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(4)
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(4)
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293T Cells
(2)
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(2)
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(2)
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Purified
(1)
ADCK4 Rabbit anti-Human Polyclonal (aa31-80) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ADCK4 Rabbit anti-Human Polyclonal (aa141-460) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ADCK4 Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADCK4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ADCK4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
ADCK4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
ADCK4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ADCK4 Rabbit anti-Human Polyclonal (aa6-55) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
ADCK4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ADCK4 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P
Unconjugated
100 µl/$412
ADCK4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
ADCK4 Mouse anti-Human Monoclonal (aa445-545) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
ADCK4 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
ADCK4 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
ADCK4 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
ADCK4 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
ADCK4 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
ADCK4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
ADCK4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
ADCK4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
ADCK4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
ADCK4 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
ADCK4 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
ADCK4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ADCK4 Rabbit anti-Human Polyclonal (aa231-544) Antibody
Human
WB
Unconjugated
100 µl/$450
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of 32
product results
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