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ADAMTS17 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined.
Gene Name: | ADAM metallopeptidase with thrombospondin type 1 motif, 17 |
Family/Subfamily: | Protease , Metallopeptidase M12B |
Synonyms: | ADAMTS17, ADAM-TS 17, ADAM-TS17, ADAMTS-17 |
Target Sequences: | NM_139057 NP_620688.2 Q8TE56 |
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