ADAM22

ADAM metallopeptidase domain 22

ADAM22 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

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Proteins (2)

Type

Recombinant (2)

Target

ADAM22 (2)

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No (2)

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GST (1)

His-T7 (1)

Species

Human (2)

Source

E. coli (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ADAM22 Protein (Recombinant GST) (Full Length) - LS-G33921

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

65.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ADAM22 Protein (Recombinant His-T7) (aa370-582) - LS-G26056

Source:

E. coli

Tag:

His-T7

Molecular Weight:

27.0 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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