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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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ADAM19
ADAM metallopeptidase domain 19
ADAM19 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease.
| Gene Name: | ADAM metallopeptidase domain 19 |
| Family/Subfamily: | Protease , Metallopeptidase M12B |
| Synonyms: | ADAM19, ADAM 19, FKSG34, Meltrin beta, Meltrin-beta, MLTNB, MADDAM |
| Target Sequences: | NM_023038 NP_075525.2 Q9H013 |
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