ADAM15

ADAM metallopeptidase domain 15

Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.

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Products

Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

ADAM15 (9)

Publications

No (9)

Tag

GST (2)

GST, N-terminus (1)

His (4)

Myc-DDK (Flag) (2)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

CHO Cells (1)

E. coli (2)

HEK 293 Cells (1)

Human Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (3)

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Human ADAM15 Protein (Recombinant GST) (Full Length) - LS-G31311

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

110.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ADAM15 Protein (Recombinant GST, N-terminus) (aa301-410) - LS-G60851

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ADAM15 Protein (Recombinant His) (Met1-Thr696) - LS-G98507

Source:

CHO Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

54 kDa

Price:

20 µg/$600

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Human ADAM15 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81567

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

87.72 kDa

Price:

20 µg/$150

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ADAM15 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117072

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

87.72 kDa

Price:

100 µg/$494

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Human ADAM15 Protein (Recombinant GST) (aa207-452) - LS-G22135

Source:

E. coli

Tag:

GST

Molecular Weight:

54 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human ADAM15 Protein (Recombinant His) (Met1-Thr696) - LS-G98508

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

54 kDa

Price:

20 µg/$600

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Mouse ADAM15 Protein (Recombinant His) (Met1-Thr697) - LS-G98696

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

74.6 kDa

Price:

100 µg/$843

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Human ADAM15 Protein (Recombinant His) (aa211-451) - LS-G16042

Source:

E. coli

Tag:

His

Molecular Weight:

27.3 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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