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ADAM12

ADAM metallopeptidase domain 12

ADAM12 is a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.

Gene Name: ADAM metallopeptidase domain 12
Family/Subfamily: Protease , Metallopeptidase M12B
Synonyms: ADAM12, ADAM 12, MCMPMltna, MCMP, MLTN, Meltrin-alpha, MLTNA
Target Sequences: NM_003474 NP_003465.3 O43184

Publications (1)

1
Disintegrin and metalloproteinases (ADAMs) expression in gastroesophageal reflux disease and in esophageal adenocarcinoma. T Kauttu, H Mustonen, S Vainionpää, L Krogerus, I Ilonen, J Räsänen, J Salo, P Puolakkainen. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2017 January;19:58-66. [Full Text Article] [PubMed:27026568] Related Antibodies: LS-B2756.

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Antibodies (45)
Primary (45)
ADAM12 (45)
Human (44)
Mouse (13)
Rat (10)
Bovine (4)
Dog (3)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (4)
Pig (4)
Rabbit (4)
IHC (8)
IHC-P (4)
WB (31)
ELISA (12)
ICC (1)
IF (3)
IP (3)
Peptide-ELISA (4)
rabbit (37)
mouse (3)
goat (3)
sheep (2)
Product Group
IHCPlus (2)
IgG (19)
IgG1 (1)
IgG3,k (1)
monoclonal mc (3)
polyclonal pc (42)
11n1 (1)
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APC Conjugated (2)
Biotin Conjugated (5)
Cy3 Conjugated (1)
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HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (26)
aa513-767 (8)
aa216-265 (4)
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ADAM12 Antibody - Anti-ADAM12 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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ADAM12 Goat anti-Human Polyclonal (aa2-14) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
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ADAM12 Mouse anti-Human Monoclonal (11n1) Antibody
Human
IP
Unconjugated
100 µg/$896
ADAM12 Antibody - Immunohistochemistry (IHC) analysis of ADAM12 antibody in paraffin-embedded human breast carcinoma tissue at 1:50, showing cytoplasmic,membrane and nuclear staining. Negative control (the right) using PBS instead of primary antibody. Secondary antibody is Goat An.
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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ADAM12 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
ADAM12 Antibody - Western Blot analysis of ADAM12 expression in transfected 293T cell line by ADAM12 monoclonal antibody (M01), clone 1G3.Lane 1: ADAM12 transfected lysate (Predicted MW: 80.4 KDa).Lane 2: Non-transfected lysate.
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ADAM12 Mouse anti-Human Monoclonal (1G3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
ADAM12 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using ADAM12 Antibody at dilution of 1:100
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
ADAM12 Antibody - Immunohistochemistry of paraffin-embedded Human prostate cancer using ADAM12 Polyclonal Antibody at dilution of 1:40.
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ADAM12 Sheep anti-Human Polyclonal (aa29-513) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$930
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
ADAM12 Antibody - ADAM12 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADAM12 Rabbit anti-Human Polyclonal (aa216-265) Antibody
Human
WB
Unconjugated
100 µl/$424
ADAM12 Antibody - ADAM12 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADAM12 Rabbit anti-Human Polyclonal (aa216-265) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ADAM12 Antibody - Immunochemical staining of human ADAM12 in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
ADAM12 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ADAM12 Antibody - Immunofluorescence staining of ADAM12 in Hela cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-Human ADAM12 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
ADAM12 Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ADAM12 Antibody - ADAM12 antibody (0.3 ug/ml) staining of Mouse Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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ADAM12 Goat anti-Human Polyclonal (aa225-239) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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ADAM12 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
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ADAM12 Goat anti-Mouse Polyclonal (aa740-752) Antibody
Mouse
Peptide-ELISA
Unconjugated
100 µg/$401
ADAM12 Antibody - Western blot of ADAM12 antibody.
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ADAM12 Rabbit anti-Human Polyclonal (aa513-767) Antibody
Human
WB
Unconjugated
100 µl/$275; 200 µl/$303; 500 µl/$396; 1 ml/$443; 2 ml/$535; 5 ml/$907
ADAM12 Antibody - Western blot analysis of ADAM12 expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
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ADAM12 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).