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ADA / Adenosine Deaminase

adenosine deaminase

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

Gene Name: adenosine deaminase
Synonyms: ADA, Adenosine deaminase, ADA1, Adenosine aminohydrolase
Target Sequences: NM_000022 NP_000013.2 P00813

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Proteins (11)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (7)
ADA / Adenosine Deaminase (11)
SDS-PAGE (1)
No (11)
6His, N-terminus (1)
GST (1)
His (2)
His, N-Terminal (2)
His,C-terminus (1)
His-GST (1)
His-SUMO (1)
Myc-DDK (Flag) (2)
E. coli (2)
Human (8)
293T Cells (1)
Baculovirus (1)
E. coli (5)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (1)
Biologically active (1)
ADA / Adenosine Deaminase Protein
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E. coli
His
Biologically active
50 µg/$411; 250 µg/$985; 10 µg/$276
ADA / Adenosine Deaminase Protein
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Baculovirus
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The secreted recombinant human ADA consists of 373 amino acids and predicts a molecular mass of 42.1 kDa. The apparent molecular mass of the protein is approximately 44 kDa in SDS-PAGE under reducing conditions.
50 µg/$441
ADA / Adenosine Deaminase Protein
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E. coli
6His, N-terminus
41 kDa
10 µg/$265; 100 µg/$365; 50 µg/$315
ADA / Adenosine Deaminase Protein - Recombinant Adenosine Deaminase By SDS-PAGE
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E. coli
His-GST
57.2 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
ADA / Adenosine Deaminase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
40.6 kDa
20 µg/$150
ADA / Adenosine Deaminase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.6 kDa
100 µg/$494
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HEK 293 Cells
His, N-Terminal
~41 kDa
200 µl/$283
Select
HEK 293 Cells
His, N-Terminal
~41 kDa
100 µg/$298
ADA / Adenosine Deaminase Protein
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E. coli
His-SUMO
52.4 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
ADA / Adenosine Deaminase Protein - 12.5% SDS-PAGE of human ADA stained with Coomassie Blue
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Wheat Germ Extract
GST
65.45 kDa
10 µg/$479; 25 µg/$670
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E. coli
His
27.7 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).