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ACVRL1
activin A receptor type II-like 1
Activin A receptor, type II-like 1 (also called activin receptor-like kinase 1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The protein (sometimes termed ALK1) shares similar domain structures with 3 other closely related ALK proteins (ALK2, ALK3, and ALK4) that together form a subfamily of receptor serine/threonine kinases. ACVRL1 is most highly expressed in human placenta and lung. ACVRL1 deficiency causes hemorrhagic telangiectasia type 2 (HHT2; MIM 600376) also known as Rendu-Osler-Weber syndrome 2 (ORW2).
| Gene Name: | activin A receptor type II-like 1 |
| Family/Subfamily: | Protein Kinase , Activin/TGFb |
| Synonyms: | ACVRL1, ALK1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, HHT, HHT2, SKR3, TSR-I, ORW2 |
| Target Sequences: | NM_000020 NP_000011.2 P37023 |
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ACVRL1 Rabbit anti-Human Polyclonal (aa196-245) Antibody
Mouse, Rat, Human
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
ACVRL1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
ACVRL1 Rabbit anti-Human Polyclonal (aa38-68) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ACVRL1 Rabbit anti-Human Polyclonal (aa474-503) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ACVRL1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
ACVRL1 Rabbit anti-Human Polyclonal (21-70 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ACVRL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
ACVRL1 Rabbit anti-Human Monoclonal (Preservative Free) (104) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
ACVRL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ACVRL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µg/$331
ACVRL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$412
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
ACVRL1 Rabbit anti-Human Polyclonal (aa38-68) Antibody
Mouse, Human
Flo, IHC, WB
Unconjugated
200 µl/$734
ACVRL1 Rabbit anti-Human Polyclonal (aa38-68) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa38-68) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa38-68) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa38-68) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa38-68) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa474-503) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
ACVRL1 Rabbit anti-Human Polyclonal (aa474-503) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa474-503) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa474-503) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa474-503) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal (aa474-503) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
ACVRL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
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