ACTN4

actinin, alpha 4

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

ACTN4 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human ACTN4 Protein (Recombinant GST) (Full Length) - LS-G27347

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

131.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ACTN4 Protein (Recombinant GST, N-terminus) (aa592-701) - LS-G57686

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ACTN4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67966

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.7 kDa

Price:

20 µg/$1,107

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Human ACTN4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81102

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.7 kDa

Price:

20 µg/$150

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ACTN4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116314

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.7 kDa

Price:

100 µg/$494

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Human ACTN4 Protein (Recombinant His-T7) (aa1-269) - LS-G24700

Source:

E. coli

Tag:

His-T7

Molecular Weight:

34.2 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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