Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
ACSL4 / FACL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
Gene Name: | acyl-CoA synthetase long-chain family member 4 |
Synonyms: | ACSL4, Acyl-CoA synthetase 4, ACS4, FACL4, LACS4, LACS 4, Lignoceroyl-CoA synthase, MRX63, MRX68 |
Target Sequences: | NM_004458 NP_004449.1 O60488 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.