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ACSL4 / FACL4

acyl-CoA synthetase long-chain family member 4

ACSL4 / FACL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.

Gene Name: acyl-CoA synthetase long-chain family member 4
Synonyms: ACSL4, Acyl-CoA synthetase 4, ACS4, FACL4, LACS4, LACS 4, Lignoceroyl-CoA synthase, MRX63, MRX68
Target Sequences: NM_004458 NP_004449.1 O60488

Publications (2)

1
Human cytomegalovirus inhibits apoptosis by proteasomal-mediated degradation of Bax at ER-mitochondrial contacts. Nagpal JK, Dasgupta S, Jadallah S, Chae YK, Ratovitski EA, Toubaji A, Netto GJ, Eagle T, Nissan A, Sidransky D, Trink B. Journal of virology. 2013 [PubMed:23487455] Related Antibodies: LS-C98511.
2
Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia. Kirkwood A Pritchard Jr, Xigang Jing, Michelle Teng, Clive Wells, Shuang Jia, Adeleye J Afolayan, Jason Jarzembowski, Billy W Day, Stephen Naylor, Martin J Hessner, G Ganesh Konduri, Ru-Jeng Teng. PloS one. 2022 August;17:e0269564. [Full Text Article] [PubMed:36018859] [PMC:PMC9417039] Related Antibodies: LS-B5818.

☰ Filters
Products
Antibodies (29)
Primary (29)
ACSL4 / FACL4 (29)
Human (29)
Mouse (7)
Rat (5)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Hamster (1)
Horse (4)
Monkey (4)
Pig (4)
Rabbit (4)
IHC (18)
IHC-P (10)
WB (28)
ELISA (17)
ICC (6)
IF (8)
IP (1)
Peptide-ELISA (2)
rabbit (28)
goat (1)
Product Group
IHCPlus (2)
IgG (25)
polyclonal pc (29)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (13)
aa236-267 (7)
aa28-56 (7)
N-Terminus (4)
aa250-300 (1)
aa658-670 (1)
No (27)
Yes (2)
ACSL4 / FACL4 Antibody - Anti-ACSL4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ACSL4 / FACL4 Antibody - Anti-ACSL4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ACSL4 / FACL4 Antibody - Anti-ACSL4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ACSL4 / FACL4 Antibody - Anti-ACSL4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ACSL4 / FACL4 Antibody - Anti-ACSL4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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ACSL4 / FACL4 Goat anti-Human Polyclonal (aa658-670) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
ACSL4 / FACL4 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa236-267) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa236-267) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa236-267) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa236-267) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa236-267) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa236-267) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa236-267) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
ACSL4 / FACL4 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
ACSL4 / FACL4 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
ACSL4 / FACL4 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
ACSL4 / FACL4 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
ACSL4 / FACL4 Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ACSL4 / FACL4 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using ACSL4 Polyclonal Antibody at dilution of 1:60.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa28-56) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa28-56) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa28-56) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa28-56) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa28-56) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa28-56) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ACSL4 / FACL4 Antibody - Detection of human ACSL4 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ACSL4 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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ACSL4 / FACL4 Rabbit anti-Human Polyclonal (aa250-300) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Viewing 1-25 of 29 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).