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ACP5 / TRAP

acid phosphatase 5, tartrate resistant

Acid phosphatase 5 is an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. ACP5 is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. It is expressed at high levels by osteoclasts, macrophages and dendritic cells. Two forms circulating in human blood are derived from different cell types and have different functions. 5a is derived from macrophages and dendritic cells and is a marker of inflammatory conditions. 5b is derived from osteoclasts and is a marker of bone resorption.

Gene Name: acid phosphatase 5, tartrate resistant
Synonyms: ACP5, SPENCDI, TrATPase, Type 5 acid phosphatase, Tartrate-resistant acid ATPase, TR-AP, TRACP5b
Target Sequences: NM_001611 NP_001602.1 P13686

Publications (2)

1
Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification. Till Seime, Asim Cengiz Akbulut, Moritz Lindquist Liljeqvist, Antti Siika, Hong Jin, Greg Winski, Rick H van Gorp, Eva Karlöf, Mariette Lengquist, Andrew J Buckler, Malin Kronqvist, Olivia J Waring, Jan H N Lindeman, Erik A L Biessen, Lars Maegdefessel, Anton Razuvaev, Leon J Schurgers, Ulf Hedin, Ljubica Matic. Cells. 2021 May;10: [Full Text Article] [PubMed:34063989] [PMC:PMC8224064]
2
Dual roles of heparanase in human carotid plaque calcification. Silvia Aldi, Linnéa Eriksson, Malin Kronqvist, Mariette Lengquist, Marie Löfling, Lasse Folkersen, Ljubica P Matic, Lars Maegdefessel, Karl-Henrik Grinnemo, Jin-Ping Li, C Österholm, Ulf Hedin. Atherosclerosis. 2019 Apr;283:127-136. [Full Text Article] [PubMed:30665614]

☰ Filters
Products
Proteins (18)
Over-Expression Lysate (8)
Recombinant (10)
ACP5 / TRAP (18)
No (18)
GST (1)
GST, N-terminus (2)
His (4)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (9)
Human (10)
Mouse (2)
Rabbit (1)
Rat (1)
293T Cells (4)
E. coli (4)
HEK 293 Cells (5)
Human Cells (2)
Wheat Germ Extract (3)
Purified (1)
Low endotoxin level (2)
ACP5 / TRAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.6 kDa
20 µg/$150
ACP5 / TRAP Protein - Recombinant Acid Phosphatase 5, Tartrate Resistant By SDS-PAGE
Select
E. coli
His
31.8 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
ACP5 / TRAP Protein - Recombinant Acid Phosphatase 5, Tartrate Resistant By SDS-PAGE
Select
E. coli
His
29.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
ACP5 / TRAP Protein - Recombinant Acid Phosphatase 5, Tartrate Resistant By SDS-PAGE
Select
E. coli
His-GST
59.8 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
ACP5 / TRAP Protein - Recombinant Acid Phosphatase 5, Tartrate Resistant By SDS-PAGE
Select
E. coli
His-T7
33.1 kDa
10 µg/$280; 50 µg/$432; 100 µg/$692; 200 µg/$865; 1 mg/$1,966; 500 µg/$1,510; 5 mg/$3,025; 2 mg/$2,153
ACP5 / TRAP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ACP5 / TRAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.6 kDa
20 µg/$150
ACP5 / TRAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.6 kDa
20 µg/$150
ACP5 / TRAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.6 kDa
20 µg/$150
ACP5 / TRAP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
35.8 kDa
20 µg/$600
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
35 kDa
20 µg/$600
ACP5 / TRAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.6 kDa
100 µg/$494
ACP5 / TRAP Protein - Purified recombinant protein ACP5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
34.3 kDa
20 µg/$1,107
ACP5 / TRAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.6 kDa
100 µg/$494
ACP5 / TRAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.6 kDa
100 µg/$494
ACP5 / TRAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.6 kDa
100 µg/$494
ACP5 / TRAP Protein - 12.5% SDS-PAGE of human ACP5 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
63 kDa
2 µg/$439
Viewing 1-18 of 18 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).