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ACO2 / Aconitase 2

aconitase 2, mitochondrial

ACO2 / Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Gene Name: aconitase 2, mitochondrial
Synonyms: ACO2, ACONM, Aconitase 2, Aconitase 2, mitochondrial, Citrate hydro-lyase, ICRD
Target Sequences: NM_001098 NP_001089.1 Q99798

Publications (1)

1
PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. Goo CK, Lim HY, Ho QS, Too HP, Clement MV, Wong KP. PloS one. 2012 7:e45806. [PubMed:23049865] [PMC:PMC3458951]

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Products
Antibodies (49)
Primary (49)
ACO2 / Aconitase 2 (49)
Human (48)
Mouse (19)
Rat (17)
Bat (3)
Bovine (3)
Chicken (4)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
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Pig (3)
Rabbit (3)
IHC (19)
IHC-P (8)
WB (43)
Flo (6)
ELISA (15)
IF (10)
IP (4)
Peptide-ELISA (5)
rabbit (35)
mouse (10)
goat (4)
Product Group
IHCPlus (3)
IgG (24)
IgG1 (7)
IgG2a (2)
IgG2a,k (1)
monoclonal mc (10)
polyclonal pc (39)
1A11 (1)
755CT20.2.6 (1)
OTI3G10 (2)
OTI3G8 (2)
OTI7A11 (2)
OTI7G4 (2)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (6)
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FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (31)
aa438-467 (7)
aa108-157 (4)
Internal (1)
Internal Region (1)
aa294-325 (1)
aa350-400 (1)
aa541-555 (1)
aa554-566 (1)
aa650-700 (1)
No (49)
ACO2 / Aconitase 2 Antibody - Anti-ACO2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal (aa438-467) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
ACO2 / Aconitase 2 Antibody - Anti-ACO2 / Aconitase 2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
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ACO2 / Aconitase 2 Goat anti-Human Polyclonal (aa541-555) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
ACO2 / Aconitase 2 Antibody - Immunohistochemistry image of paraffin-embedded human kidney tissue at a dilution of 1:100
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
ACO2 / Aconitase 2 Antibody - Anti-ACO2 / Aconitase 2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
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ACO2 / Aconitase 2 Goat anti-Human Polyclonal (aa554-566) Antibody
Chicken, Human, Monkey
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
ACO2 / Aconitase 2 Antibody - Biotinylated antibody (0.1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer), exactly mirroring its parental non-biotinylated product. Primary incubation was 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP block
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ACO2 / Aconitase 2 Goat anti-Human Polyclonal (Internal Region) (Biotin) Antibody
Human
IF, IHC, Peptide-ELISA, WB
Biotin Conjugated
100 µg/$503
ACO2 / Aconitase 2 Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-ACO2 mouse monoclonal antibody. (Dilution 1:50).
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ACO2 / Aconitase 2 Mouse anti-Human Monoclonal (OTI3G8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ACO2 / Aconitase 2 Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-ACO2 mouse monoclonal antibody. (Dilution 1:50).
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ACO2 / Aconitase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI3G8) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ACO2 / Aconitase 2 Antibody - Anti-ACO2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACO2.
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ACO2 / Aconitase 2 Mouse anti-Human Monoclonal (OTI7A11) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ACO2 / Aconitase 2 Antibody - Anti-ACO2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACO2.
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ACO2 / Aconitase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI7A11) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ACO2 / Aconitase 2 Antibody - Anti-ACO2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACO2.
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ACO2 / Aconitase 2 Mouse anti-Human Monoclonal (OTI7G4) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ACO2 / Aconitase 2 Antibody - Anti-ACO2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACO2.
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ACO2 / Aconitase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI7G4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
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ACO2 / Aconitase 2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$412
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$412
ACO2 / Aconitase 2 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using ACO2 Polyclonal Antibody at dilution of 1:30.
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal (aa438-467) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal (aa438-467) (Biotin) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal (aa438-467) (FITC) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal (aa438-467) (APC) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal (aa438-467) (Azide-free) (HRP) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal (aa438-467) (PE) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ACO2 / Aconitase 2 Antibody - Anti-ACO2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACO2.
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ACO2 / Aconitase 2 Mouse anti-Human Monoclonal (OTI3G10) Antibody
Human
Flo, IF
Unconjugated
100 µl/$434
ACO2 / Aconitase 2 Antibody - Anti-ACO2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACO2.
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ACO2 / Aconitase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI3G10) Antibody
Human
Flo, IF
Unconjugated, Carrier-free
100 µg/$511
ACO2 / Aconitase 2 Antibody - Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ACO2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal (aa294-325) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ACO2 / Aconitase 2 Antibody - 1:100 staining human lymph carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ACO2 / Aconitase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).