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May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.
Gene Name: | AE binding protein 1 |
Family/Subfamily: | Exopeptidase , Metallopeptidase M14 |
Synonyms: | AEBP1, AE binding protein 1, ACLP, AE-binding protein 1 |
Target Sequences: | NM_001129 NP_001120.3 Q8IUX7 |
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