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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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ACKR4 / CCRL1 / CCR11

atypical chemokine receptor 4

Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Chemokine-binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization. Plays an important role in controlling the migration of immune and cancer cells that express chemokine receptors CCR7 and CCR9, by reducing the availability of CCL19, CCL21, and CCL25 through internalization. Negatively regulates CXCR3-induced chemotaxis. Regulates T-cell development in the thymus.

Gene Name: atypical chemokine receptor 4
Family/Subfamily: GPCR , Chemokine
Synonyms: ACKR4, C-C CKR-11, CC-CKR-11, CC chemokine receptor-like 1, CCR11, CCX CKR, C-C chemokine receptor type 11, CKR-11, CCRL1, VSHK1, CCR-11, CCX-CKR, PPR1
Target Sequences: NM_016557 NP_057641.1 Q9NPB9

☰ Filters
Products
ELISA Kits (13)
Competitive EIA (1)
Sandwich (10)
Sandwich CLIA (2)
ACKR4 / CCRL1 / CCR11 (13)
Human (1)
Mouse (4)
Rat (3)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (2)
96-Well Strip Plate (9)
No (13)
Plasma (8)
Serum (8)
Tissue Homogenates (2)
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Rat
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ACKR4 / CCRL1 / CCR11 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Viewing 1-13 of 13 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).