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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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ACKR4 / CCRL1 / CCR11
atypical chemokine receptor 4
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Chemokine-binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization. Plays an important role in controlling the migration of immune and cancer cells that express chemokine receptors CCR7 and CCR9, by reducing the availability of CCL19, CCL21, and CCL25 through internalization. Negatively regulates CXCR3-induced chemotaxis. Regulates T-cell development in the thymus.
| Gene Name: | atypical chemokine receptor 4 |
| Family/Subfamily: | GPCR , Chemokine |
| Synonyms: | ACKR4, C-C CKR-11, CC-CKR-11, CC chemokine receptor-like 1, CCR11, CCX CKR, C-C chemokine receptor type 11, CKR-11, CCRL1, VSHK1, CCR-11, CCX-CKR, PPR1 |
| Target Sequences: | NM_016557 NP_057641.1 Q9NPB9 |
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Fast Shipping
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Human
IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (260-340 aa, C-terminal) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (20-100 aa, N-terminal) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (aa5-54) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACKR4 / CCRL1 / CCR11 Goat anti-Human Polyclonal (aa4-31) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$556
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (aa291-340) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (aa47-96) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Bovine, Pig, Gibbon, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Bovine, Pig, Gibbon, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Bovine, Pig, Gibbon, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$299
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ACKR4 / CCRL1 / CCR11 Mouse anti-Human Monoclonal (1G4) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$595
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
100 µl/$386
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Sandwich
96-Well Microplate
Rat
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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