ACER2

alkaline ceramidase 2

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Unsaturated long-chain ceramides are the best substrates, saturated long-chain ceramides and unsaturated very long-chain ceramides are good substrates, whereas saturated very long-chain ceramides and short-chain ceramides were poor substrates. The substrate preference is D-erythro-C(18:1)-, C(20:1)-, C(20:4)-ceramide > D-erythro-C(16:0)-, C(18:0), C(20:0)-ceramide > D-erythro-C(24:1)-ceramide > D-erythro-C(12:0)-ceramide, D-erythro-C(14:0)-ceramides > D-erythro-C(24:0)-ceramide > D-erythro-C(6:0)-ceramide. Inhibits the maturation of protein glycosylation in the Golgi complex, including that of integrin beta-1 (ITGB1) and of LAMP1, by increasing the levels of sphingosine. Inhibits cell adhesion by reducing the level of ITGB1 in the cell surface. May have a role in cell proliferation and apoptosis that seems to depend on the balance between sphingosine and sphingosine-1-phosphate.

☰ Filters

Products

Antibodies (10)

Type

Primary (10)

Target

ACER2 (10)

Reactivity

Human (10)

Mouse (8)

Rat (5)

Bat (3)

Bovine (3)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (5)

Pig (3)

Rabbit (3)

more less

Application

IHC (1)

WB (10)

ELISA (2)

IF (1)

Peptide-ELISA (1)

Host

rabbit (10)

Isotype

IgG (2)

Clonality

polyclonal pc (10)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (7)

Epitope

aa93-142 (4)

Internal (1)

Publications

No (9)

Yes (1)

Select

ACER2 Antibody (Internal) LS-C354506

(4.0) Rating

(1) Publication(s)

Antibody:

ACER2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

ACER2 Antibody LS-C813327

Antibody:

ACER2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

ACER2 Antibody (aa93-142) LS-C152143

Antibody:

ACER2 Rabbit anti-Human Polyclonal (aa93-142) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

ACER2 Antibody (aa93-142, HRP) LS-C473793

Antibody:

ACER2 Rabbit anti-Human Polyclonal (aa93-142) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ACER2 Antibody (aa93-142, Biotin) LS-C473791

Antibody:

ACER2 Rabbit anti-Human Polyclonal (aa93-142) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ACER2 Antibody (aa93-142, FITC) LS-C473792

Antibody:

ACER2 Rabbit anti-Human Polyclonal (aa93-142) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ACER2 Antibody LS-C804784

Antibody:

ACER2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ACER2 Antibody LS-C415683

Antibody:

ACER2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

ACER2 Antibody LS-C659032

Antibody:

ACER2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

Select

ACER2 Antibody LS-C411963

Antibody:

ACER2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Viewing 1-10 of 10 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Antibodies

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.