ACER1 / ASAH3

alkaline ceramidase 1

Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]; Sun et al., 2008 [PubMed 17713573]).

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Products

Antibodies (22)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (22)

Recombinant (1)

Target

ACER1 / ASAH3 (25)

Reactivity

Human (22)

Mouse (2)

Rat (2)

Bovine (3)

Chimpanzee (6)

Gibbon (6)

Guinea pig (3)

Monkey (4)

Rabbit (3)

Application

IHC (2)

WB (21)

ELISA (10)

IF (1)

Peptide-ELISA (1)

Host

rabbit (22)

Isotype

IgG (9)

Clonality

polyclonal pc (22)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (11)

Epitope

aa236-263 (7)

C-Terminus (4)

aa141-190 (4)

Internal (1)

N-Terminus (1)

Publications

No (25)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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ACER1 / ASAH3 Antibody LS-C807721

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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ACER1 / ASAH3 Antibody LS-C137315

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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ACER1 / ASAH3 Antibody LS-C829990

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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ACER1 / ASAH3 Antibody (N-Terminus) LS-C47019

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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ACER1 / ASAH3 Antibody (aa236-263) LS-C319277

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa236-263) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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ACER1 / ASAH3 Antibody (aa236-263, Biotin) LS-C232363

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa236-263) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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ACER1 / ASAH3 Antibody (aa236-263, FITC) LS-C232365

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa236-263) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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ACER1 / ASAH3 Antibody (aa236-263, Azide-free, HRP) LS-C249364

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa236-263) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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ACER1 / ASAH3 Antibody (aa236-263, APC) LS-C232364

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa236-263) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

ACER1 / ASAH3 Antibody (aa236-263, PE) LS-C232366

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa236-263) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

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ACER1 / ASAH3 Antibody LS-C813325

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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ACER1 / ASAH3 Antibody LS-C340938

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

ACER1 / ASAH3 Antibody (aa141-190) LS-C135888

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa141-190) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ACER1 / ASAH3 Antibody (aa141-190, HRP) LS-C467985

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa141-190) (HRP) Antibody

Reactivity:

Rabbit, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ACER1 / ASAH3 Antibody (aa141-190, Biotin) LS-C467983

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa141-190) (Biotin) Antibody

Reactivity:

Rabbit, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ACER1 / ASAH3 Antibody (aa141-190, FITC) LS-C467984

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa141-190) (FITC) Antibody

Reactivity:

Rabbit, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ACER1 / ASAH3 Antibody (C-Terminus) LS-C135889

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

ACER1 / ASAH3 Antibody (C-Terminus, HRP) LS-C467988

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Human, Chimpanzee, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ACER1 / ASAH3 Antibody (C-Terminus, Biotin) LS-C467986

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human, Chimpanzee, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ACER1 / ASAH3 Antibody (C-Terminus, FITC) LS-C467987

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human, Chimpanzee, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ACER1 / ASAH3 Antibody (aa236-263) LS-C160997

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (aa236-263) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

ACER1 / ASAH3 Antibody (Internal) LS-C353859

Antibody:

ACER1 / ASAH3 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

Human ACER1 / ASAH3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93174

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.9 kDa

Price:

20 µg/$150

Select

Human ACER1 / ASAH3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72655

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.9 kDa

Price:

20 µg/$1,107

Select

ACER1 / ASAH3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107529

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.9 kDa

Price:

100 µg/$494

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