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ACE / CD143

angiotensin I converting enzyme

ACE / CD143 is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Gene Name: angiotensin I converting enzyme
Family/Subfamily: Protease , Metallopeptidase M2
Synonyms: ACE, ACE1, Angiotensin-converting enzyme, CD143, CD143 antigen, Carboxycathepsin, DIPEPTIDYL CARBOXYPEPTIDASE, DCP, Dipeptidyl carboxypeptidase I, ICH, Kininase II, MVCD3, Peptidyl-dipeptidase A, Peptidase P, DCP1, Dipeptidyl carboxypeptidase 1, Testicular ECA
Target Sequences: NM_000789 NP_000780.1 P12821

☰ Filters
Products
Proteins (12)
Native (1)
Over-Expression Lysate (2)
Recombinant (9)
ACE / CD143 (12)
No (12)
GST, N-terminus (1)
His, N-Terminal (1)
His-GST (3)
His-MBP (1)
His-S (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
Mouse (3)
Pig (1)
Rabbit (2)
293T Cells (1)
E. coli (7)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Biologically active (1)
ACE / CD143 Protein
Select
E. coli
His-GST
61.5 kDa
10 µg/$272; 50 µg/$385; 100 µg/$615; 200 µg/$770; 1 mg/$1,828; 500 µg/$1,388; 5 mg/$2,788; 2 mg/$2,010
ACE / CD143 Protein - Recombinant Angiotensin I Converting Enzyme By SDS-PAGE
Select
E. coli
His-T7
20.3 kDa
10 µg/$272; 50 µg/$385; 100 µg/$615; 200 µg/$770; 1 mg/$1,828; 500 µg/$1,388; 5 mg/$2,788; 2 mg/$2,010
ACE / CD143 Protein - Recombinant Angiotensin I Converting Enzyme By SDS-PAGE
Select
E. coli
His-MBP
55.2 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
ACE / CD143 Protein
Select
E. coli
His-S
14.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
ACE / CD143 Protein - Recombinant Angiotensin I Converting Enzyme By SDS-PAGE
Select
E. coli
His-GST
52.0 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
Select
E. coli
His-GST
37.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
None
Biologically active
129 kDa, 140 kDa
0.25 Unit/$437
ACE / CD143 Protein - Purified recombinant protein ACE was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
79.1 kDa
20 µg/$1,107
ACE / CD143 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ACE / CD143 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
79.1 kDa
20 µg/$215
ACE / CD143 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
79.1 kDa
100 µg/$710
Select
E. coli
His, N-Terminal
26.6kDa
10 µg/$287; 50 µg/$482; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,841
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).