ACD / PTOP

adrenocortical dysplasia homolog (mouse)

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis.

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Products

Antibodies (51)

Proteins (12)

ELISA Kits (6)

Type

Over-Expression Lysate (6)

Primary (51)

Recombinant (6)

Sandwich (6)

Target

ACD / PTOP (69)

Reactivity

Human (43)

Mouse (17)

Rat (13)

Bovine (6)

Chicken (1)

Chimpanzee (3)

Dog (6)

Guinea pig (7)

Horse (6)

Monkey (4)

Porcine (1)

Rabbit (1)

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Application

IHC (3)

IHC-P (2)

WB (48)

Flo (2)

ELISA (5)

IF (5)

IP (1)

Host

rabbit (43)

mouse (8)

Isotype

IgG (24)

IgG1 (4)

IgG1,k (1)

IgG2b (2)

Clonality

monoclonal mc (7)

polyclonal pc (44)

Clone

1D8-1B6 (1)

OTI1A2 (2)

OTI1C8 (2)

OTI2B1 (2)

Format

96-Well Strip Plate (6)

APC (2)

APC Conjugated (3)

Biotin Conjugated (7)

Carrier-free (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (3)

Unconjugated (20)

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Epitope

aa147-342 (8)

aa21-175 (8)

C-Terminus (4)

aa398-447 (4)

aa467-516 (4)

aa66-348 (1)

Publications

No (68)

Yes (1)

Sample Type

Plasma (1)

Serum (1)

Tag

GST (1)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (8)

Species

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (2)

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ACD / PTOP Antibody (aa467-516) LS-C108067

(4.0) Rating

(1) Publication(s)

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal (aa467-516) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ACD / PTOP Antibody (clone 1D8-1B6) LS-C133807

Antibody:

ACD / PTOP Mouse anti-Human Monoclonal (1D8-1B6) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

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ACD / PTOP Antibody (clone OTI2B1) LS-C173789

Antibody:

ACD / PTOP Mouse anti-Human Monoclonal (OTI2B1) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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ACD / PTOP Antibody (clone OTI2B1, Carrier-free) LS-C786954

Antibody:

ACD / PTOP Mouse anti-Human Monoclonal (Carrier-free) (OTI2B1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ACD / PTOP Antibody (clone OTI1A2) LS-C337656

Antibody:

ACD / PTOP Mouse anti-Human Monoclonal (OTI1A2) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

ACD / PTOP Antibody (clone OTI1A2, Carrier-free) LS-C786966

Antibody:

ACD / PTOP Mouse anti-Human Monoclonal (Carrier-free) (OTI1A2) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ACD / PTOP Antibody (clone OTI1C8) LS-C337608

Antibody:

ACD / PTOP Mouse anti-Human Monoclonal (OTI1C8) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

ACD / PTOP Antibody (clone OTI1C8, Carrier-free) LS-C786812

Antibody:

ACD / PTOP Mouse anti-Human Monoclonal (Carrier-free) (OTI1C8) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ACD / PTOP Antibody LS-C137335

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$332

Select

ACD / PTOP Antibody LS-C659907

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

ACD / PTOP Antibody LS-C672419

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

ACD / PTOP Antibody LS-C831232

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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ACD / PTOP Antibody (C-Terminus) LS-C115987

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

ACD / PTOP Antibody (C-Terminus, HRP) LS-C434775

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Horse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ACD / PTOP Antibody (C-Terminus, Biotin) LS-C434774

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Horse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ACD / PTOP Antibody (C-Terminus, FITC) LS-C434773

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Horse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ACD / PTOP Antibody (aa21-175) LS-C374385

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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ACD / PTOP Antibody (aa21-175, HRP) LS-C711280

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

Select

ACD / PTOP Antibody (aa21-175, Biotin) LS-C686932

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

ACD / PTOP Antibody (aa21-175, APC) LS-C717688

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

ACD / PTOP Antibody (aa21-175, PE) LS-C725339

Antibody:

ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• HRP
• Biotin
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • APC
  • PE

Select

ACD / PTOP Antibody (aa66-348) LS-C311880

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal (aa66-348) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$414

Select

ACD / PTOP Antibody LS-C309294

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

ACD / PTOP Antibody LS-C747350

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

ACD / PTOP Antibody (aa398-447) LS-C82017

Antibody:

ACD / PTOP Rabbit anti-Human Polyclonal (aa398-447) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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