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ACCN4 / ASIC4
acid-sensing (proton-gated) ion channel family member 4
ACCN4 / ASIC4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
| Gene Name: | acid-sensing (proton-gated) ion channel family member 4 |
| Family/Subfamily: | Ion Channel , Sodium channel - amiloride-sensitive |
| Synonyms: | ASIC4, ACCN4, Acid-sensing ion channel 4, BNAC4, Brain sodium channel 4, Spasic |
| Target Sequences: | NM_018674 |
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