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ACADSB

acyl-CoA dehydrogenase, short/branched chain

Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa.

Gene Name: acyl-CoA dehydrogenase, short/branched chain
Synonyms: ACADSB, 2-MEBCAD, ACAD7, SBCAD
Target Sequences: NM_001609 NP_001600.1 P45954

Publications (1)

1
Metabolic Response to Heat Stress in Late-Pregnant and Early Lactation Dairy Cows: Implications to Liver-Muscle Crosstalk. Koch F, Lamp O, Eslamizad M, Weitzel J, Kuhla B. PloS one. 2016 11:e0160912. (WB; Human) [Full Text Article] [PubMed:27513961] [PMC:PMC4981427] Related Antibodies: LS-C81878.

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Proteins (4)
Over-Expression Lysate (2)
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ACADSB (4)
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Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
ACADSB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
47.46 kDa
20 µg/$150
ACADSB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
47.46 kDa
100 µg/$494
ACADSB Protein - 12.5% SDS-PAGE of human ACADSB stained with Coomassie Blue
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Wheat Germ Extract
GST
73.26 kDa
10 µg/$479; 25 µg/$670
ACADSB Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).