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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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ACADL

acyl-CoA dehydrogenase, long chain

Long-chain acyl-coA dehydrogenase (ACADL), also abbreviated as LCAD, is a mitochondrial metrix enzyme involved in catalyzing the first reaction in the mitochondrial beta-oxidation cycles for fatty acids. Two other acyl-coA dehydrogenases are also involved in fatty acid oxidation, medium chain and short chain ALDs. However, of these ACADL catalyzes the first and critical step in this process. ACADL is a homotetrameic enzyme of 45-kD. It is synthesized in the cytoplasm a a precursor then processed and targeted to the mitochondria. Genetic deficiency of ACADL is associated with severe hypoglycemia, skeletal muscle weakness, hepatomegaly and cardiomegaly, which can be fatal.

Gene Name: acyl-CoA dehydrogenase, long chain
Synonyms: ACADL, ACAD4, LCAD
Target Sequences: NM_001608 NP_001599.1 P28330

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ACADL ELISA Kit
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0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$730
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).