ABRI / ITM2B

integral membrane protein 2B

Plays a regulatory role in the processing of the beta-amyloid A4 precursor protein (APP) and acts as an inhibitor of the beta-amyloid peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites.Mature BRI2 (mBRI2) functions as a modulator of the beta-amyloid A4 precursor protein (APP) processing leading to a strong reduction in the secretion of secretase-processed beta-amyloid protein 40 and beta-amyloid protein 42.Bri23 peptide prevents aggregation of APP beta-amyloid protein 42 peptide into toxic oligomers.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

ABRI / ITM2B (7)

Publications

No (7)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

HEK 293 Cells (2)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human ABRI / ITM2B Protein (Recombinant 6His, C-terminus) (Tyr76-Ser266) - LS-G39123

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

23.3kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human ABRI / ITM2B Protein (Recombinant GST) (Full Length) - LS-G31634

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

56.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ABRI / ITM2B Protein (Recombinant GST, N-terminus) (aa146-245) - LS-G61130

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ABRI / ITM2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85724

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.2 kDa

Price:

20 µg/$150

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Human ABRI / ITM2B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69872

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.2 kDa

Price:

20 µg/$1,107

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ABRI / ITM2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110528

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.2 kDa

Price:

100 µg/$494

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Human ABRI / ITM2B Protein (Recombinant 6His, C-terminus) (Tyr76-Ser266) - LS-G140224

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

23.3 kDa

Price:

10 µg/$317; 50 µg/$524

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