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ABRI / ITM2B
integral membrane protein 2B
Plays a regulatory role in the processing of the beta-amyloid A4 precursor protein (APP) and acts as an inhibitor of the beta-amyloid peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites.Mature BRI2 (mBRI2) functions as a modulator of the beta-amyloid A4 precursor protein (APP) processing leading to a strong reduction in the secretion of secretase-processed beta-amyloid protein 40 and beta-amyloid protein 42.Bri23 peptide prevents aggregation of APP beta-amyloid protein 42 peptide into toxic oligomers.
| Gene Name: | integral membrane protein 2B |
| Synonyms: | ITM2B, ABri/ADan amyloid peptide, ABRI, BRI, BRI2, E3-16, Integral membrane protein 2B, ImBRI2, FBD, Protein E25B, BRICD2B, BRICHOS domain containing 2B, Transmembrane protein BRI, E25B, Immature BRI2 |
| Target Sequences: | NM_021999 NP_068839.1 Q9Y287 |
☰ Filters
Products
Antibodies
(31)
Type
Primary
(31)
Target
ABRI / ITM2B
(31)
Reactivity
Human
(26)
Mouse
(16)
Rat
(2)
Bovine
(1)
Horse
(1)
Monkey
(2)
Rabbit
(5)
Application
IHC
(13)
IHC-P
(4)
WB
(27)
Flo
(2)
ELISA
(16)
IF
(1)
Peptide-ELISA
(1)
Host
rabbit
(21)
mouse
(9)
goat
(1)
Product Group
IHCPlus
(1)
Isotype
IgG
(20)
IgG2a
(2)
IgG2a,k
(6)
Clonality
monoclonal mc
(8)
polyclonal pc
(23)
Clone
OTI1C11
(2)
Format
APC Conjugated
(3)
Azide-free
(1)
Biotin Conjugated
(4)
Carrier-free
(1)
FITC Conjugated
(4)
HRP Conjugated
(4)
PE Conjugated
(3)
Unconjugated
(13)
Epitope
aa218-247
(7)
Internal
(1)
aa146-245
(1)
aa224-238
(1)
Publications
No
(31)
ABRI / ITM2B Goat anti-Human Polyclonal (aa224-238) Antibody
Bovine, Horse, Human, Monkey
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
ABRI / ITM2B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ABRI / ITM2B Rabbit anti-Human Polyclonal (aa218-247) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ABRI / ITM2B Mouse anti-Human Monoclonal (OTI1C11) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ABRI / ITM2B Mouse anti-Human Monoclonal (Carrier-free) (OTI1C11) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ABRI / ITM2B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
ABRI / ITM2B Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
ABRI / ITM2B Rabbit anti-Human Polyclonal (aa218-247) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
ABRI / ITM2B Rabbit anti-Mouse Polyclonal (aa218-247) (Biotin) Antibody
Mouse
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
ABRI / ITM2B Rabbit anti-Mouse Polyclonal (aa218-247) (FITC) Antibody
Mouse
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
ABRI / ITM2B Rabbit anti-Mouse Polyclonal (aa218-247) (APC) Antibody
Mouse
ELISA, IHC, WB
APC Conjugated
200 µl/$952
ABRI / ITM2B Rabbit anti-Mouse Polyclonal (aa218-247) (PE) Antibody
Mouse
ELISA, IHC, WB
PE Conjugated
200 µl/$952
ABRI / ITM2B Rabbit anti-Mouse Polyclonal (aa218-247) (Azide-free) (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ABRI / ITM2B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ABRI / ITM2B Mouse anti-Human Monoclonal (aa146-245) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
ABRI / ITM2B Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
ABRI / ITM2B Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
ABRI / ITM2B Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
ABRI / ITM2B Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
ABRI / ITM2B Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
ABRI / ITM2B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ABRI / ITM2B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
ABRI / ITM2B Rabbit anti-Human Polyclonal (Biotin) Antibody
Rabbit, Mouse, Human
WB
Biotin Conjugated
100 µl/$937
ABRI / ITM2B Rabbit anti-Human Polyclonal (APC) Antibody
Rabbit, Mouse, Human
WB
APC Conjugated
100 µl/$937
ABRI / ITM2B Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25
of 31
product results
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