ABI1 / SSH3BP1

abl-interactor 1

May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.

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Products

Proteins (17)

Type

Over-Expression Lysate (12)

Recombinant (5)

Target

ABI1 / SSH3BP1 (17)

Publications

No (17)

Tag

GST, N-terminus (1)

His-S (1)

Myc-DDK (Flag) (15)

Species

Human (11)

Source

293T Cells (6)

E. coli (1)

HEK 293 Cells (9)

Wheat Germ Extract (1)

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Human ABI1 / SSH3BP1 Protein (Recombinant GST, N-terminus) (aa185-238) - LS-G61319

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80095

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.3 kDa

Price:

20 µg/$215

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Human ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80097

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.31 kDa

Price:

20 µg/$215

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Human ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80096

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.7 kDa

Price:

20 µg/$150

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Human ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80098

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.4 kDa

Price:

20 µg/$150

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Human ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80099

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

20 µg/$150

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Human ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80100

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

20 µg/$150

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Human ABI1 / SSH3BP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67541

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.9 kDa

Price:

20 µg/$1,107

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Human ABI1 / SSH3BP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67542

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

20 µg/$1,107

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Human ABI1 / SSH3BP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67543

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.7 kDa

Price:

20 µg/$1,107

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ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129631

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

100 µg/$494

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ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129885

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

100 µg/$494

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ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129912

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.4 kDa

Price:

100 µg/$494

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ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121360

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.7 kDa

Price:

100 µg/$494

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ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121362

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.3 kDa

Price:

100 µg/$710

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ABI1 / SSH3BP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100560

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.31 kDa

Price:

100 µg/$710

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Human ABI1 / SSH3BP1 Protein (Recombinant His-S) (aa1-182) - LS-G26018

Source:

E. coli

Tag:

His-S

Molecular Weight:

24.3 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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