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ABI1 / SSH3BP1

abl-interactor 1

May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.

Gene Name: abl-interactor 1
Synonyms: ABI1, Abelson interactor 1, Abl-interactor protein 1 long, ABI-1, Abl-interactor 1, Abl interactor 1, Abl-binding protein 4, ABLBP4, NAP1BP, Nap1 binding protein, SSH3BP1, Nap1-binding protein, E3B1, Eps8-binding protein, Interactor protein AblBP4, SSH3BP
Target Sequences: NM_005470 NP_005461.2 Q8IZP0

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Products
Proteins (17)
Over-Expression Lysate (12)
Recombinant (5)
ABI1 / SSH3BP1 (17)
No (17)
GST, N-terminus (1)
His-S (1)
Myc-DDK (Flag) (15)
Human (11)
293T Cells (6)
E. coli (1)
HEK 293 Cells (9)
Wheat Germ Extract (1)
ABI1 / SSH3BP1 Protein - Recombinant  Abl Interactor 1 By SDS-PAGE
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E. coli
His-S
24.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
52.3 kDa
20 µg/$215
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293T Cells
Myc-DDK (Flag)
51.7 kDa
20 µg/$150
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
49.31 kDa
20 µg/$215
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
54.4 kDa
20 µg/$150
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
52.8 kDa
20 µg/$150
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.4 kDa
20 µg/$150
ABI1 / SSH3BP1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ABI1 / SSH3BP1 Protein - Purified recombinant protein ABI1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
54.9 kDa
20 µg/$1,107
ABI1 / SSH3BP1 Protein - Purified recombinant protein ABI1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
36.4 kDa
20 µg/$1,107
ABI1 / SSH3BP1 Protein - Purified recombinant protein ABI1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
51.7 kDa
20 µg/$1,107
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
49.31 kDa
100 µg/$710
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51.7 kDa
100 µg/$494
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
52.3 kDa
100 µg/$710
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.4 kDa
100 µg/$494
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
52.8 kDa
100 µg/$494
ABI1 / SSH3BP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
54.4 kDa
100 µg/$494
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).