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ABHD12

Abhydrolase Domain Containing 12

ABHD12 is an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene Name: Abhydrolase Domain Containing 12
Synonyms: ABHD12, ABHD12A, BEM46L2, C20orf22, DKFZP434P106, PHARC, DJ965G21.2, Monoacylglycerol lipase ABHD12
Target Sequences: NM_001042472 NP_001035937.1 Q8N2K0

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Products
Antibodies (21)
Primary (21)
ABHD12 (21)
Human (20)
Mouse (9)
Rat (10)
Bat (3)
Bovine (6)
Chimpanzee (3)
Dog (6)
Guinea pig (3)
Horse (6)
Monkey (7)
Rabbit (6)
IHC (3)
IHC-P (2)
WB (21)
Flo (1)
ELISA (7)
IF (1)
Peptide-ELISA (3)
rabbit (19)
mouse (1)
goat (1)
Product Group
IHCPlus (1)
IgG (11)
polyclonal pc (21)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (10)
aa40-66 (7)
C-Terminus (4)
aa323-372 (4)
200-280 aa, Internal (1)
aa231-280 (1)
aa348-360 (1)
No (21)
ABHD12 Antibody - Formalin-fixed and paraffin-embedded human testis tissue reacted with ABHD12 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ABHD12 Rabbit anti-Human Polyclonal (aa40-66) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ABHD12 Antibody - Anti-ABHD12 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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ABHD12 Rabbit anti-Human Polyclonal (aa231-280) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
ABHD12 Antibody - Western blot of ABHD12 antibody
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ABHD12 Rabbit anti-Human Polyclonal (200-280 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ABHD12 Antibody - ABHD12 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABHD12 Rabbit anti-Human Polyclonal (aa323-372) Antibody
Human
WB
Unconjugated
100 µl/$424
ABHD12 Antibody - ABHD12 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABHD12 Rabbit anti-Human Polyclonal (aa323-372) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ABHD12 Antibody - ABHD12 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABHD12 Rabbit anti-Human Polyclonal (aa323-372) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ABHD12 Antibody - ABHD12 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABHD12 Rabbit anti-Human Polyclonal (aa323-372) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
ABHD12 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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ABHD12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ABHD12 Rabbit anti-Human Polyclonal (aa40-66) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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ABHD12 Rabbit anti-Human Polyclonal (aa40-66) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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ABHD12 Rabbit anti-Human Polyclonal (aa40-66) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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ABHD12 Rabbit anti-Human Polyclonal (aa40-66) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ABHD12 Rabbit anti-Human Polyclonal (aa40-66) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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ABHD12 Rabbit anti-Human Polyclonal (aa40-66) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ABHD12 Antibody - Antibody (0.3 ug/ ml) staining of Mouse Brain lysate (35 ug/ protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
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ABHD12 Goat anti-Human Polyclonal (aa348-360) Antibody
Mouse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
ABHD12 Antibody - ABHD12 antibody Western blot of Mouse Thymus lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABHD12 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$424
ABHD12 Antibody - ABHD12 antibody Western blot of Mouse Thymus lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABHD12 Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ABHD12 Antibody - ABHD12 antibody Western blot of Mouse Thymus lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABHD12 Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ABHD12 Antibody - ABHD12 antibody Western blot of Mouse Thymus lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABHD12 Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
WB
FITC Conjugated
100 µl/$469
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ABHD12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$289
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ABHD12 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-21 of 21 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).