ABCG8

ATP-binding cassette, sub-family G (WHITE), member 8

ABCG8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

ABCG8 (4)

Publications

No (4)

Tag

His-T7, N-terminus (2)

Myc-DDK (Flag) (2)

Species

Human (1)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

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Human ABCG8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91627

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75.5 kDa

Price:

20 µg/$215

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ABCG8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110390

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75.5 kDa

Price:

100 µg/$710

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Rat ABCG8 Protein (Recombinant His-T7, N-terminus) (Met1-Gln271) - LS-G133547

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

34.1kDa

Price:

10 µg/$276; 50 µg/$412; 200 µg/$822; 100 µg/$657; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Mouse ABCG8 Protein (Recombinant His-T7, N-terminus) (Met1-Gln272) - LS-G133442

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

34.0kDa

Price:

10 µg/$275; 50 µg/$402; 200 µg/$802; 100 µg/$642; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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