ABCG5

ATP-binding cassette, sub-family G (WHITE), member 5

ABCG5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.

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Proteins (1)

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Recombinant (1)

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ABCG5 (1)

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Mouse (1)

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E. coli (1)

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Mouse ABCG5 Protein (Recombinant) (Asp66-Gly276) - LS-G133677

Source:

E. coli

Tag:

None

Molecular Weight:

27.2kDa

Price:

10 µg/$292; 50 µg/$512; 200 µg/$1,018; 100 µg/$817; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359

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