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Abcg3
ATP-binding cassette, sub-family G (WHITE), member 3
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It lacks several highly conserved residues found in other ATP-binding proteins; this suggests that this protein may not bind ATP and may require dimerization with another subunit to form a functional ATP-transporter. The function of this gene has not yet been determined; however, high levels of expression in the thymus and spleen suggest a potential role in the transport of specific peptides or hydrophobic compounds from lymphocytes.
| Gene Name: | ATP-binding cassette, sub-family G (WHITE), member 3 |
| Family/Subfamily: | Transporter , ATP-binding cassette - ABCG/WHITE |
| Synonyms: | Abcg3, Abcp2, Mxr2 |
| Target Sequences: | AF324242 AAK14241.1 Q99P81 |
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