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ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.

Gene Name: ATP-binding cassette, sub-family G (WHITE), member 1
Family/Subfamily: Transporter , ATP-binding cassette - ABCG/WHITE
Synonyms: ABCG1, ABC transporter 8, ABC transporter, ABC8, Homolog of Drosophila white, White protein homolog, WHITE1, WHT1
Target Sequences: NM_004915 NP_004906.3 P45844

Publications (3)

1
Expression, localization, and functional model of cholesterol transporters in lactating and nonlactating mammary tissues of murine, bovine, and human origin. Mani O, Krner M, Sorensen MT, Sejrsen K, Wotzkow C, Ontsouka CE, Friis RR, Bruckmaier RM, Albrecht C. American journal of physiology. Regulatory, integrative and comparative physiology. 2010 299:R642-54. (IHC-P; Mouse, Bovine, Human) [PubMed:20445153]
2
Identification of ABCA1 and ABCG1 in milk fat globules and mammary cells--implications for milk cholesterol secretion. Mani O, Körner M, Ontsouka CE, Sorensen MT, Sejrsen K, Bruckmaier RM, Albrecht C. Journal of dairy science. 2011 March;94:1265-1276. [Full Text Article] [PubMed:21338792] Related Antibodies: LS-B507.
3
Elastic aortic wrap reduced aortic stiffness by partially alleviating the impairment of cholesterol efflux capacity in pigs. Shutan Liao, Qing Zhou, Yang Zhang. Journal of diabetes and metabolic disorders. 2018 December;17:101-109. [Full Text Article] [PubMed:30918842] [PMC:PMC6405383] Related Antibodies: LS-C313008.

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Proteins (4)
Recombinant (4)
ABCG1 (4)
No (4)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (1)
Human (4)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
ABCG1 Protein - Recombinant ATP Binding Cassette Transporter G1 By SDS-PAGE
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E. coli
His
27.3 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
ABCG1 Protein - 12.5% SDS-PAGE of human ABCG1 stained with Coomassie Blue
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Wheat Germ Extract
GST
102 kDa
2 µg/$439
ABCG1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ABCG1 Protein - Purified recombinant protein ABCG1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
74 kDa
20 µg/$1,107
Viewing 1-4 of 4 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).