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ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
Gene Name: | ATP-binding cassette, sub-family G (WHITE), member 1 |
Family/Subfamily: | Transporter , ATP-binding cassette - ABCG/WHITE |
Synonyms: | ABCG1, ABC transporter 8, ABC transporter, ABC8, Homolog of Drosophila white, White protein homolog, WHITE1, WHT1 |
Target Sequences: | NM_004915 NP_004906.3 P45844 |
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