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ABCC8 / SUR1
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not yet been fully described.
| Gene Name: | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| Family/Subfamily: | Transporter , ATP-binding cassette - ABCC/MRP |
| Synonyms: | ABCC8, ABC36, HI, PHHI, Sulfonylurea receptor, SUR, Sulfonylurea receptor 1, MRP8, SUR1delta2, HHF1, HRINS, SUR1, TNDM2 |
| Target Sequences: | NM_000352 NP_000343.2 Q09428 |
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Antibodies
(40)
Type
Primary
(40)
Target
ABCC8 / SUR1
(40)
Reactivity
Human
(29)
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(17)
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(18)
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(3)
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(1)
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(1)
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(3)
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(3)
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(21)
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(6)
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(32)
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(11)
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rabbit
(25)
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(12)
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(11)
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(11)
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monoclonal mc
(12)
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(28)
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(1)
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(1)
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(1)
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(4)
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(1)
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(1)
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(1)
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(1)
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(4)
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(3)
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(1)
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(1)
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(1)
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(17)
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aa1548-1582
(9)
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(8)
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(4)
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(1)
Publications
No
(40)
ABCC8 / SUR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ABCC8 / SUR1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ABCC8 / SUR1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ABCC8 / SUR1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
ABCC8 / SUR1 Mouse anti-Human Monoclonal (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Unconjugated
100 µg/$442
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (Biotin) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Biotin Conjugated
100 µg/$475
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (FITC) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
FITC Conjugated
100 µg/$472
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (Atto 390) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Atto 390 Conjugated
100 µg/$479
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (Atto 488) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Atto 488 Conjugated
100 µg/$479
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (Atto 594) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Atto 594 Conjugated
100 µg/$479
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (APC) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
APC Conjugated
100 µg/$478
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (PerCP) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
PerCP Conjugated
100 µg/$478
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (RPE) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
RPE Conjugated
100 µg/$477
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Unconjugated
100 µg/$665
ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ABCC8 / SUR1 Mouse anti-Human Monoclonal (3E1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, WB
Unconjugated
100 µg/$575
ABCC8 / SUR1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
ABCC8 / SUR1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (S289-16) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$537
ABCC8 / SUR1 Goat anti-Human Polyclonal (aa1559-1571) Antibody
Dog, Bovine, Horse, Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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of 40
product results
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