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Vector Laboratories, Inc.
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ABCC8 / SUR1

ATP-binding cassette, sub-family C (CFTR/MRP), member 8

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not yet been fully described.

Gene Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Family/Subfamily: Transporter , ATP-binding cassette - ABCC/MRP
Synonyms: ABCC8, ABC36, HI, PHHI, Sulfonylurea receptor, SUR, Sulfonylurea receptor 1, MRP8, SUR1delta2, HHF1, HRINS, SUR1, TNDM2
Target Sequences: NM_000352 NP_000343.2 Q09428

☰ Filters
Antibodies (40)
Proteins (3)
ELISA Kits (1)
Primary (40)
Recombinant (3)
Sandwich (1)
ABCC8 / SUR1 (44)
Human (30)
Mouse (17)
Rat (18)
Bat (3)
Bovine (4)
Dog (1)
Hamster (10)
Horse (1)
Monkey (4)
Pig (3)
Rabbit (3)
IHC (21)
IHC-P (6)
WB (32)
Flo (4)
ELISA (4)
ICC (11)
IF (2)
Peptide-ELISA (2)
rabbit (25)
mouse (12)
goat (1)
rabbit-new zealand white (2)
Product Group
IHCPlus (1)
IgG (11)
IgG1 (11)
IgG1,k (1)
monoclonal mc (12)
polyclonal pc (28)
3E1 (1)
S289-16 (11)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (2)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 594 Conjugated (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (1)
PerCP Conjugated (1)
RPE Conjugated (1)
Unconjugated (17)
aa1548-1582 (9)
aa679-929 (8)
N-Terminus (4)
aa1559-1571 (1)
No (44)
Cell Lysates (1)
Tissue Homogenates (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (1)
Human (3)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
ABCC8 / SUR1 Antibody - Anti-ABCC8 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ABCC8 / SUR1 Antibody - Anti-ABCC8 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ABCC8 / SUR1 Antibody - Anti-ABCC8 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ABCC8 / SUR1 Antibody - Anti-ABCC8 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ABCC8 / SUR1 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ABCC8 / SUR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
ABCC8 / SUR1 Antibody - Western blot - Anti-SUR1 Picoband antibody
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
ABCC8 / SUR1 Antibody - Immunohistochemistry image at a dilution of 1:500 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
ABCC8 / SUR1 Protein - Recombinant ATP Binding Cassette Transporter C8 By SDS-PAGE
Select
E. coli
His
31.9 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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ABCC8 / SUR1 Mouse anti-Human Monoclonal (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Unconjugated
100 µg/$442
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ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (Biotin) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Biotin Conjugated
100 µg/$475
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ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (FITC) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
FITC Conjugated
100 µg/$472
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ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (Atto 488) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Atto 488 Conjugated
100 µg/$479
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ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (Atto 594) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Atto 594 Conjugated
100 µg/$479
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ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (APC) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
APC Conjugated
100 µg/$478
Select
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (PerCP) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
PerCP Conjugated
100 µg/$478
Select
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (RPE) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
RPE Conjugated
100 µg/$477
Select
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (Atto 390) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Atto 390 Conjugated
100 µg/$479
Select
ABCC8 / SUR1 Mouse anti-Rat Monoclonal (aa1548-1582) (S289-16) Antibody
Mouse, Rat, Hamster
ICC, IHC, WB
Unconjugated
100 µg/$665
ABCC8 / SUR1 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using ABCC8 Polyclonal Antibody at dilution of 1:40.
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ABCC8 / SUR1 Antibody - Detection limit for recombinant GST tagged ABCC8 is 0.03 ng/ml as a capture antibody.
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ABCC8 / SUR1 Mouse anti-Human Monoclonal (3E1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
ABCC8 / SUR1 Antibody - Western blot testing of 1) human placenta, 2) rat brain and 3) mouse brain lysate with SUR1 antibody at 0.5ug/ml. Predicted molecular weight ~177 kDa.
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ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, WB
Unconjugated
100 µg/$575
Select
ABCC8 / SUR1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
Select
ABCC8 / SUR1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
Select
ABCC8 / SUR1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 44 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).