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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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ABCC6 / MRP6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCC6 / MRP6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
| Gene Name: | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| Family/Subfamily: | Transporter , ATP-binding cassette - ABCC/MRP |
| Synonyms: | ABCC6, ABC34, EST349056, MLP1, MOAT-E, MRP6, MOATE, URG7, PXE1, ARA, GACI2, Pseudoxanthoma elasticum, PXE |
| Target Sequences: | NM_001171 NP_001162.4 O95255 |
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