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Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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ABCC4 / MRP4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC4 / MRP4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.
| Gene Name: | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| Family/Subfamily: | Transporter , ATP-binding cassette - ABCC/MRP |
| Synonyms: | ABCC4, EST170205, MOAT-B, Multidrug resistance protein 4, MOATB, MRP4 |
| Target Sequences: | NM_005845 NP_005836.2 O15439 |
Publications (4)
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