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ABCC3 / MRP3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

ABCC3 / MRP3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Gene Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Family/Subfamily: Transporter , ATP-binding cassette - ABCC/MRP
Synonyms: ABCC3, ABC31, EST90757, MOAT-D, MLP2, Multidrug resistance protein 3, MRP3, CMOAT2
Target Sequences: NM_003786 AAD02845.1 O15438

Publications (1)

1
Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia. Kleberg K, Jensen GM, Christensen DP, Lundh M, Grunnet LG, Knuhtsen S, Poulsen SS, Hansen MB, Bindslev N. BMC gastroenterology. 2012 12:78. (IHC; Human) [Full Text Article] [PubMed:22734885] [PMC:PMC3457850] Related Antibodies: LS-C16477.

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ABCC3 / MRP3 (3)
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His-T7 (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
ABCC3 / MRP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
169.2 kDa
20 µg/$215
ABCC3 / MRP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
169.2 kDa
100 µg/$710
ABCC3 / MRP3 Protein - Recombinant  ATP Binding Cassette TransPorter C3 By SDS-PAGE
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E. coli
His-T7
29.5 kDa
10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).