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ABCC3 / MRP3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

ABCC3 / MRP3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Gene Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Family/Subfamily: Transporter , ATP-binding cassette - ABCC/MRP
Synonyms: ABCC3, ABC31, EST90757, MOAT-D, MLP2, Multidrug resistance protein 3, MRP3, CMOAT2
Target Sequences: NM_003786 AAD02845.1 O15438

Publications (1)

1
Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia. Kleberg K, Jensen GM, Christensen DP, Lundh M, Grunnet LG, Knuhtsen S, Poulsen SS, Hansen MB, Bindslev N. BMC gastroenterology. 2012 12:78. (IHC; Human) [Full Text Article] [PubMed:22734885] [PMC:PMC3457850] Related Antibodies: LS-C16477.

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ABCC3 / MRP3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
ABCC3 / MRP3 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ABCC3 / MRP3 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
ABCC3 / MRP3 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
ABCC3 / MRP3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).