ABCB11 / BSEP

ATP-binding cassette, sub-family B (MDR/TAP), member 11

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

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Proteins (2)

Type

Recombinant (2)

Target

ABCB11 / BSEP (2)

Publications

No (2)

Tag

His, N-Terminal (1)

His-T7 (1)

Species

Human (1)

Mouse (1)

Source

E. coli (2)

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Human ABCB11 / BSEP Protein (Recombinant His, N-Terminal) (aa421-663) - LS-G25340

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

30.5 kDa

Price:

10 µg/$272; 50 µg/$385; 100 µg/$615; 200 µg/$770; 1 mg/$1,828; 500 µg/$1,388; 5 mg/$2,788; 2 mg/$2,010

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Mouse ABCB11 / BSEP Protein (Recombinant His-T7) (aa420-656) - LS-G15337

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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