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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.
Gene Name: | ATP-binding cassette, sub-family A (ABC1), member 6 |
Family/Subfamily: | Transporter , ATP-binding cassette - ABCA/ABC1 |
Synonyms: | ABCA6, ABC transporter ABCA6, ATP-binding cassette A6, EST155051 |
Target Sequences: | NM_080284 NP_525023.2 Q8N139 |
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