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AASS / LKR / SDH

aminoadipate-semialdehyde synthase

AASS / LKR / SDH is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

Gene Name: aminoadipate-semialdehyde synthase
Synonyms: AASS, LKRSDH, LKR/SDH, LORSDH
Target Sequences: NM_005763 NP_005754.2 Q9UDR5

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AASS / LKR / SDH ELISA Kit
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).