A2M / Alpha-2-Macroglobulin

alpha-2-macroglobulin

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

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Products

ELISA Kits (27)

Type

Competitive EIA (3)

Custom (2)

Development Kit (1)

Sandwich (19)

Sandwich CLIA (2)

Target

A2M / Alpha-2-Macroglobulin (27)

Reactivity

Human (12)

Mouse (2)

Rat (5)

Bovine (2)

Chicken (1)

Monkey (2)

Rabbit (2)

Rhesus monkey (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (3)

96-Well Strip Plate (22)

Antibody Pair and Standard (1)

Publications

No (27)

Sample Type

Biological Fluids (1)

Cell Culture Supernatants (6)

Cell Lysates (2)

Cell Supernatant (1)

Plasma (25)

Serum (25)

Tissue Homogenates (10)

Urine (4)

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Human A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F2835

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

625 - 40000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

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Mouse A2M / Alpha-2-Macroglobulin (Competitive EIA) ELISA Kit - LS-F6496

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

6.17 - 500 µg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Urine

Price:

1 Plate/$617

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Human A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F9539

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$757

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Mouse A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F15624

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Rat A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F15622

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

7.8 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Biological Fluids, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$585

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Rat A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F38752

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

9.38 - 600 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Bovine A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F31820

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

0.156 - 10 µg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F4392

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Urine

Price:

1 Plate/$685

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Bovine A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F10697

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

3.12 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Human A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F3530

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

12.29 - 1200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

Select

Human A2M / Alpha-2-Macroglobulin (Custom ELISA) ELISA Kit - LS-F15623

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$585

Select

Monkey A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F38532

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$565

Select

Chicken A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F40976

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

93.75 - 6000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$565

Select

Human A2M / Alpha-2-Macroglobulin (CLIA) ELISA Kit - LS-F29664

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F35205

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.469 - 30 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F35206

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat A2M / Alpha-2-Macroglobulin (Custom ELISA) ELISA Kit - LS-F56629

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

3.13 - 800 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$1,002

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Rat A2M / Alpha-2-Macroglobulin (Competitive EIA) ELISA Kit - LS-F55522

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

123.5 - 10000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rabbit A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F56568

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

DevKit DuoPlus Human A2M / Alpha-2-Macroglobulin ELISA Development Kit - LS-F71463

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Urine

Price:

500 Wells/$1,089; 1000 Wells/$1,589

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Rhesus monkey A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F55378

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rhesus monkey

Range:

7.8 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$826

Select

Monkey A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F55849

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human A2M / Alpha-2-Macroglobulin (Competitive EIA) ELISA Kit - LS-F54458

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.25 - 20 µg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$822

Select

Human A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F74867

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$528

Select

Rabbit A2M / Alpha-2-Macroglobulin (Sandwich ELISA) ELISA Kit - LS-F22556

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rabbit

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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