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Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Gene Name: | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
Synonyms: | SRD5A1, 5-alpha reductase, SR type 1, Steroid 5-alpha-reductase 1, S5AR 1 |
Target Sequences: | NM_001047 NP_001038.1 P18405 |
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