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15-PGDH / HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
15-PGDH / HPGD is a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| Synonyms: | HPGD, 15-PGDH, PGDH, PGDH1, PHOAR1, Prostaglandin dehydrogenase 1, SDR36C1 |
| Target Sequences: | NM_000860 NP_000851.2 P15428 |
Publications (13)
1
Monoclonal antibodies that inhibit the enzyme activity of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. Tai CL, Mak OT, Arai T, Tai HH. The Biochemical journal. 1990 267:75-8. (Human)
[PubMed:1691637]
[PMC:PMC1131246]
2
Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells. Tong M, Tai HH. Endocrinology. 2004 145:2141-7.
[PubMed:14749354]
3
NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer. Ding Y, Tong M, Liu S, Moscow JA, Tai HH. Carcinogenesis. 2005 26:65-72.
[PubMed:15358636]
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15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 ml/$460
15-PGDH / HPGD Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
15-PGDH / HPGD Mouse anti-Human Monoclonal (OTI2C10) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
15-PGDH / HPGD Mouse anti-Human Monoclonal (Carrier-free) (OTI2C10) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Baboon
IHC, IHC-P, WB
Unconjugated
1 Each/$485
15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
15-PGDH / HPGD Mouse anti-Human Monoclonal (OTI1C10) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
15-PGDH / HPGD Mouse anti-Human Monoclonal (Carrier-free) (OTI1C10) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
15-PGDH / HPGD Rabbit anti-Human Polyclonal (aa205-266) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
15-PGDH / HPGD Goat anti-Human Polyclonal (aa255-266) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
15-PGDH / HPGD Mouse anti-Human Monoclonal (OTI2F5) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
15-PGDH / HPGD Mouse anti-Human Monoclonal (Carrier-free) (OTI2F5) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
15-PGDH / HPGD Mouse anti-Human Monoclonal (OTI1E9) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
15-PGDH / HPGD Mouse anti-Human Monoclonal (Carrier-free) (OTI1E9) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
15-PGDH / HPGD Rabbit anti-Human Monoclonal (Preservative Free) (004) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
15-PGDH / HPGD Rabbit anti-Human Polyclonal (aa184-212) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$649
15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IF
Unconjugated
100 µl/$412
15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IF
Unconjugated
100 µl/$412
15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
15-PGDH / HPGD Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, IP, WB
Unconjugated
100 µl/$412
15-PGDH / HPGD Mouse anti-Human Monoclonal (OTI1C12) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
15-PGDH / HPGD Mouse anti-Human Monoclonal (Carrier-free) (OTI1C12) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
15-PGDH / HPGD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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