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Search Results for “caspase”
Pages with Related Content
Overview of all products associated with Caspase 4 + Caspase 5
CASP12 (Caspase 12) is an anti-inflammatory caspase that mediates apoptosis in response to endoplasmic reticulum stress in rodents. In humans, a majority of individuals have a premature stop codon in the CASP12 gene that results in a truncated and non-functional (but expressed) translated protein. Some individuals of primarily African descent have an alternate read-through codon that results in the translation of a functional CASP12 protein. These individuals have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. CASP12 has also been found to be expressed in cancer, including multiple myeloma, gastrointestinal stromal tumors, glioblastoma and nasopharyngeal carcinoma cells. In immunohistochemistry, CASP12 has cytoplasmic (endoplasmic reticulum) positivity in the small intestine, heart, spleen, stomach, kidney, liver, lung, pancreas, thymus and testis.
References: Nature. 2004. 429 (6987): 75–9, PMID: 15129283; Proc. Natl. Acad. Sci. U.S.A. 106 (22): 9016–20, PMID: 19447924; Oncotarget. 2017 May 16; 8(20): 33515–33526, PMID: 28380444; Immunol Lett. 2016 May;173:21-5, PMID: 26973091
Overview of all products associated with CASP14 / Caspase 14
Viewing 1-3
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Type
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(9)
Cell-Based Phosphorylation
(10)
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(7)
Custom
(22)
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Development Kit
(16)
Over-Expression Cell Culture Supernatant
(2)
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(93)
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(161)
Sandwich
(179)
Sandwich CLIA
(23)
Target
AIMP1 / EMAP II
(1)
AVEN / PDCD12
(32)
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(2)
BCL10 / BCL-10
(8)
BCL2 / Bcl-2
(3)
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(2)
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rabbit
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(69)
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(2)
PathPlus Neuro
(4)
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(859)
IgG1
(67)
IgG1,k
(64)
IgG2a
(32)
IgG2a,k
(24)
IgG2b
(8)
IgG2b,k
(38)
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(1)
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(1)
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monoclonal mc
(313)
polyclonal pc
(999+)
Clone
02
(1)
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(1)
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(1)
11B4
(1)
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(1)
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(6)
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12 x 8-Well Microstrips
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(46)
96-Well Strip Plate
(182)
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(98)
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(17)
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(16)
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(3)
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(58)
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(58)
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(2)
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(1)
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(159)
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(153)
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(3)
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(111)
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Ready-to-Use
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(3)
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(46)
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(37)
aa29-175
(32)
aa81-270
(20)
aa81-179
(18)
aa1-200
(17)
aa120-297
(17)
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(16)
aa194-293
(16)
aa207-303
(16)
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(16)
aa25-175
(16)
aa290-377
(16)
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(15)
aa1-272
(10)
aa331-416
(10)
aa7-216
(10)
aa1-242
(9)
aa161-210
(9)
pSer196
(9)
pSer257
(9)
pSer801
(9)
aa1-134
(8)
aa1-218
(8)
aa1-244
(8)
aa1-246
(8)
aa1-257
(8)
aa1-413
(8)
aa145-327
(8)
aa17-248
(8)
aa170-325
(8)
aa170-333
(8)
aa210-460
(8)
aa217-384
(8)
aa219-376
(8)
aa223-459
(8)
aa26-283
(8)
aa274-530
(8)
aa286-373
(8)
aa317-404
(8)
aa331-411
(8)
aa334-452
(8)
aa385-479
(8)
aa43-281
(8)
aa701-808
(8)
aa8-197
(8)
aa81-266
(8)
aa87-323
(8)
aa944-1148
(8)
pSer1126
(8)
aa1-30
(7)
aa149-179
(7)
aa165-193
(7)
aa17-45
(7)
aa235-263
(7)
aa265-294
(7)
aa283-311
(7)
aa37-65
(7)
aa518-546
(7)
aa78-106
(7)
pSer12
(7)
pSer26
(7)
aa198-226
(6)
aa301-350
(6)
pSer1176
(6)
pSer1501
(6)
pSer748
(6)
aa1-80
(5)
aa110-159
(5)
aa122-168
(5)
aa149-175
(5)
aa151-200
(5)
aa180-229
(5)
aa281-330
(5)
pSer150
(5)
pSer347
(5)
aa1-480
(4)
aa1-92
(4)
aa107-156
(4)
aa143-192
(4)
aa2-452
(4)
aa20-69
(4)
aa211-260
(4)
aa251-300
(4)
aa287-336
(4)
aa30-79
(4)
aa467-516
(4)
aa51-100
(4)
aa601-650
(4)
aa80-129
(4)
pSer376
(4)
pThr125
(4)
120-200 aa, Internal
(3)
90-170 aa
(3)
Cleaved-Asp175
(3)
N-Terminal
(3)
aa126-175
(3)
aa205-222
(3)
pTyr380
(3)
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No
(999+)
Yes
(13)
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Microplate fluorometer
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(93)
Urine
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6His, C-terminus
(4)
6His, N-terminus
(10)
GST
(19)
GST, N-terminus
(30)
His
(30)
His, N-Terminal
(13)
His,N-terminus
(1)
His-GST
(4)
His-GST, N-terminus
(1)
His-S
(1)
His-SUMO
(2)
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(22)
His-T7, N-terminus
(1)
Myc-DDK (Flag)
(114)
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(1)
TRX-6His, N-terminus
(1)
Species
Bovine
(5)
Human
(177)
Mouse
(18)
Pig
(1)
Rat
(10)
Source
293T Cells
(46)
E. coli
(88)
HEK 293 Cells
(73)
Wheat Germ Extract
(48)
Yeast
(1)
Purification
Purified
(31)
Low Endotoxin Level
Low endotoxin level
(6)
Neuroscience
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$440
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal (aa100-116) Antibody
Mouse
WB
Unconjugated
100 µg/$386
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
CASP12 / Caspase 12 Rat Monoclonal (14F7) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$392
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa71-84) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CASP12 / Caspase 12 Rat anti-Mouse Monoclonal (aa183-205) (12G6) Antibody
Mouse
ELISA, Flo, WB
Unconjugated
100 µg/$414
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$649
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$649
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa50-99) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
Viewing 1-25
of 2446
product results
for caspase
