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Proteins > ERBB2 / HER2 > LS-G47454
 
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Catalog Number Size Price
LS-G47454-100 100 µg $488 
LS-G47454-1 1 mg $2,393 
ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
ERBB2 / HER2 Protein
ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
ERBB2 / HER2 Protein
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Human ERBB2 / HER2 Protein (Recombinant His,C-terminus) (Met1-Thr652) - LS-G47454

Human ERBB2 / HER2 Protein (Recombinant His,C-terminus) (Met1-Thr652) - LS-G47454

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Description:
ERBB2 / HER2 Protein LS-G47454 is a Recombinant Human ERBB2 / HER2 produced in HEK 293 Cells Met1-Thr652 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Price
Catalog Number
$488
LS-G47454-100
Toll Free North America
(800) 227-6666
For Research Use Only
Specifications Publications Reviews Images Popular ERBB2 / HER2 Proteins Request SDS/MSDS

Overview

Description:
ERBB2 / HER2 Protein LS-G47454 is a Recombinant Human ERBB2 / HER2 produced in HEK 293 Cells Met1-Thr652 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only

Specifications

Type
Recombinant Protein
Target
ERBB2 / HER2
Synonyms
ERBB2 | C-erb B2/neu protein | CD340 | HER2 | Herstatin | MLN 19 | HER-2 | Neu | NGL | Proto-oncogene c-ErbB-2 | Proto-oncogene Neu | CD340 antigen | MLN19 | p185erbB2 | TKR1
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Applications
  • Binding
  • ELISA
  • Functional Assay
  • Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Tag
His,C-terminus
Region
Met1-Thr652
Predicted Molecular Weight
The recombinant human ERBB2 consists 636 amino acids and predicts a molecular mass of 70 kDa.
Expression System
HEK 293 Cells
Source Species
Human
Purification
> 95 % as determined by SDS-PAGE.
Bio-Activity
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10µg/mL (100µL/well) can bind herceptin,the EC50 of herceptin is 7-90ng/mL. Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
Please refer to included instructions for detailed information.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee
About ERBB2 / HER2
P04626 NM_004448 NP_004439.2

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Images

Binding

ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.

Proliferation

ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

ERBB2 / HER2 Protein

Binding

ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.

Proliferation

ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

ERBB2 / HER2 Protein

Binding

ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.

Proliferation

ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

ERBB2 / HER2 Protein

Binding

ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.

Proliferation

ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

ERBB2 / HER2 Protein

Popular ERBB2 / HER2 Proteins

ERBB2 / HER2 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
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ERBB2 / HER2 Protein - 12.5% SDS-PAGE of human ERBB2 stained with Coomassie Blue
Human ERBB2 / HER2 Protein (Recombinant GST) (Full Length) - LS-G28375
Source: Wheat
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Product
Human ERBB2 / HER2 Protein (Recombinant Fc, C-terminus) (Thr23-Thr652) - LS-G39502
Source: Human
Tag: Fc, C-terminus

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

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Requested From: United States
Date Requested: 12/26/2024
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United States

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