LSBio logo with text
Products
Research Areas
COVID-19
Resources
Contact Us
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Cart
How To Buy
Contact Us

Location

Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers


Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us


Additional Contact Details

Distributors
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Proteins > ERBB2 / HER2 > LS-G47454
 
Print Page  
Catalog Number Size Price
LS-G47454-100 100 µg $488 
LS-G47454-1 1 mg $2,393 
ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
ERBB2 / HER2 Protein
ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
ERBB2 / HER2 Protein
1 of 3
2 of 3
3 of 3

Human ERBB2 / HER2 Protein (Recombinant His,C-terminus) (Met1-Thr652) - LS-G47454

Human ERBB2 / HER2 Protein (Recombinant His,C-terminus) (Met1-Thr652) - LS-G47454

Submit Review LSBio Guarantee
Description:
ERBB2 / HER2 Protein LS-G47454 is a Recombinant Human ERBB2 / HER2 produced in HEK 293 Cells Met1-Thr652 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Price
Catalog Number
$488
LS-G47454-100
Toll Free North America
(800) 227-6666
For Research Use Only
Specifications Publications Reviews Images Popular ERBB2 / HER2 Proteins Request SDS/MSDS

Overview

Description:
ERBB2 / HER2 Protein LS-G47454 is a Recombinant Human ERBB2 / HER2 produced in HEK 293 Cells Met1-Thr652 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only

Specifications

Type
Recombinant Protein
Target
ERBB2 / HER2
Synonyms
ERBB2 | C-erb B2/neu protein | CD340 | HER2 | Herstatin | MLN 19 | HER-2 | Neu | NGL | Proto-oncogene c-ErbB-2 | Proto-oncogene Neu | CD340 antigen | MLN19 | p185erbB2 | TKR1
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Applications
  • Binding
  • ELISA
  • Functional Assay
  • Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Tag
His,C-terminus
Region
Met1-Thr652
Predicted Molecular Weight
The recombinant human ERBB2 consists 636 amino acids and predicts a molecular mass of 70 kDa.
Expression System
HEK 293 Cells
Source Species
Human
Purification
> 95 % as determined by SDS-PAGE.
Bio-Activity
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10µg/mL (100µL/well) can bind herceptin,the EC50 of herceptin is 7-90ng/mL. Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
Please refer to included instructions for detailed information.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee
About ERBB2 / HER2
P04626 NM_004448 NP_004439.2

Publications (0)

Submit a Publication for LS-G47454

Customer Reviews (0)

Submit a review for LS-G47454

Images

Binding

ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.

Proliferation

ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

ERBB2 / HER2 Protein

Binding

ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.

Proliferation

ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

ERBB2 / HER2 Protein

Binding

ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.

Proliferation

ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

ERBB2 / HER2 Protein

Binding

ERBB2 / HER2 Protein - Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.
Measured by its binding ability in a functional ELISA. Immobilized human ErbB2 at 10 µg/mL (100 µL/well) can bind herceptin, the EC50 of herceptin is 7-90 ng/mL.

Proliferation

ERBB2 / HER2 Protein - Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.
Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.4-2.4µg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

ERBB2 / HER2 Protein

Popular ERBB2 / HER2 Proteins

ERBB2 / HER2 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Human ERBB2 / HER2 Protein (Recombinant 6His, N-terminus) (Thr23-Thr652) - LS-G26960
Source: Human
Tag: 6His, N-terminus
ERBB2 / HER2 Protein - Recombinant Epidermal Growth Factor Receptor 2 By SDS-PAGE
Human ERBB2 / HER2 Protein (Recombinant His-GST) (aa376-578) - LS-G14420
Source: E. coli
Tag: His-GST
ERBB2 / HER2 Protein - Recombinant Epidermal Growth Factor Receptor 2 By SDS-PAGE
Human ERBB2 / HER2 Protein (Recombinant His, N-Terminal) (aa23-372) - LS-G24532
Source: E. coli
Tag: His, N-Terminal
ERBB2 / HER2 Protein - 12.5% SDS-PAGE of human ERBB2 stained with Coomassie Blue
Human ERBB2 / HER2 Protein (Recombinant GST) (Full Length) - LS-G28375
Source: Wheat
Tag: GST
Product
Human ERBB2 / HER2 Protein (Recombinant Fc, C-terminus) (Thr23-Thr652) - LS-G39502
Source: Human
Tag: Fc, C-terminus

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Family of Companies
Site Links Home All Antibodies How To Buy All Proteins Distributors All ELISA & Assay Kits Reviews PathPlus™ Antibodies
Follow LSBio View Cart Register or Login
Copyright © 2024 LifeSpan BioSciences, Inc - Privacy Policy
Contact Us

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Tel: (800) 227-6666 / (650) 697-3600

To place an order:
customerservice@vectorlabs.com

For questions about orders:
Customer.Support@LSBio.com

For technical assistance:
Technical.Support@LSBio.com