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| Catalog Number | Size | Price |
|---|---|---|
| LS-G47161-100 | 100 µg | $480 |
| LS-G47161-1 | 1 mg | $2,324 |
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Human KDR / VEGFR2 / FLK1 Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Glu764) - LS-G47161
Human KDR / VEGFR2 / FLK1 Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Glu764) - LS-G47161
Description:
KDR / VEGFR2 / FLK1 Protein LS-G47161 is a Recombinant Human KDR / VEGFR2 / FLK1 produced in HEK 293 Cells Met1-Glu764 with Human IgG Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Description:
KDR / VEGFR2 / FLK1 Protein LS-G47161 is a Recombinant Human KDR / VEGFR2 / FLK1 produced in HEK 293 Cells Met1-Glu764 with Human IgG Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
KDR / VEGFR2 / FLK1
Synonyms
KDR | CD309 | Fetal liver kinase 1 | Fetal liver kinase-1 | FLK-1 | FLK1 | Kinase insert domain receptor | Quek1 | VEGFR | VEGFR2 | Soluble VEGFR2 | VEGF receptor 2 | VEGFR-2 | CD309 antigen | VEGF-R2
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Applications
- Binding
- ELISA
- Functional Assay
- Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Tag
Human IgG Fc, C-terminus
Region
Met1-Glu764
Predicted Molecular Weight
The recombinant human VEGFR2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 979 amino acids and predicts a molecular mass of 109 kDa. The apparent molecular mass of rh VEGFR2/Fc monomer is approximatly 150-160 in SDS-PAGE under reducing conditions.
Expression System
HEK 293 Cells
Source Species
Human
Purification
> 90 % as determined by SDS-PAGE
Bio-Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant human VEGFA at 1.25 µg/ml (100 µl/well) can bind VEGFR2 with a linear range of 1.25-40.0 ng/ml. Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile PBS, pH 7.4, 5% Trehalose, 5% Mannitol, 0.01% Tween80.
Reconstitution
Reconstitute in 400ul of sterile water to a concentration of 0.25mg/ml.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About KDR / VEGFR2 / FLK1
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Proliferation
Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Proliferation
Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Proliferation
Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Proliferation
Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Popular KDR / VEGFR2 / FLK1 Proteins
Source:
E. coli
Tag:
His-S
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
