Target
PCSK9
Synonyms
PCSK9 | FH3 | HCHOLA3 | LDLCQ1 | NARC-1 | Proprotein convertase 9 | NARC1 | PC9
Modifications
Carrier-free
Conjugations
Unconjugated
Predicted Molecular Weight
Predicted molecular mass of approximately 73 kD. It migrates as 70 and 17 kD for mature and prodomain, respectively, in DTT-reducing conditions and 63 and 17 kD in non-reducing conditions by SDS-PAGE.
Expression System
CHO Cells
Source Species
Hamster-Chinese
Purification
Greater than 90% by SDS-PAGE
Bio-Activity
When recombinant human LDLR is immobilized at 1 µg/mL, recombinant human PCSK9 binds with EC50 of 0.04 - 0.2 µg/mL in a functional ELISA.
Endotoxin
Less than 1 EU/µg (determined by LAL method).
Presentation
0.22 µm filtered protein solution in 20 mM Tris, pH 8.0, 150 mM NaCl
Storage
Store unopened at 2°C to 8°C for up to 1 month, at -20°C for up to 3 months, or at -70°C for up to 6 months. Avoid freeze/thaw cycles. For maximum results, quick spin vial prior to opening.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee