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| Catalog Number | Size | Price |
|---|---|---|
| LS-G136861-20 | 20 µg | $475 |
| LS-G136861-100 | 100 µg | $1,164 |
| LS-G136861-1 | 1 mg | $2,187 |
Human XRCC5 / Ku80 Protein (Recombinant MBP, N-terminus + 6His, C-terminus) - LS-G136861
Human XRCC5 / Ku80 Protein (Recombinant MBP, N-terminus + 6His, C-terminus) - LS-G136861
Description:
XRCC5 / Ku80 Protein LS-G136861 is a Recombinant Human XRCC5 / Ku80 produced in Baculovirus 251-455aa with MBP, N-terminus + 6His, C-terminus tag(s). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
XRCC5 / Ku80 Protein LS-G136861 is a Recombinant Human XRCC5 / Ku80 produced in Baculovirus 251-455aa with MBP, N-terminus + 6His, C-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
XRCC5 / Ku80
Synonyms
XRCC5 | 86 kDa subunit of Ku antigen | CTC85 | CTCBF | DNA repair protein XRCC5 | G22P2 | KARP-1 | Ku autoantigen, 80kDa | NFIV | KARP1 | Ku86 | KUB2 | TLAA | Nuclear factor IV | KU80 | Thyroid-lupus autoantigen
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
MBP, N-terminus + 6His, C-terminus
Region
251-455aa
Predicted Molecular Weight
67.4 kDa
AA Sequence
LTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDDDETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQVLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLVYVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVD
Expression System
Baculovirus
Source Species
Baculovirus
Purification
Greater than 85% by SDS-PAGE
Usage Summary
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from Tris, 50% Glycerol
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About XRCC5 / Ku80
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Popular XRCC5 / Ku80 Proteins
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 10/19/2024
Date Requested: 10/19/2024
